Takeshima Teppei, Yamamoto Mizuki, Takamoto Daiji, Mochizuki Taku, Kuroda Shinnosuke, Kawahara Takashi, Izumi Koji, Teranishi Jun-Ichi, Miyoshi Yasuhide, Otani Masako, Uemura Hiroji, Yumura Yasushi
Department of Urology Reproduction Center Yokohama City University Medical Center Yokohama Japan.
Department of Urology and Renal Transplantation Yokohama City University Medical Center Yokohama Japan.
IJU Case Rep. 2018 Dec 24;2(2):65-68. doi: 10.1002/iju5.12037. eCollection 2019 Mar.
Testicular epidermal cysts in Klinefelter syndrome are very rare. We report a case of Klinefelter syndrome associated with a testicular epidermal cyst. To our knowledge, this is the first report showing successful spermatozoa retrieval from the affected testis.
A 25-year-old married man was referred to our hospital with right scrotal induration, which was in lower pole of the right testis. Testicular cancer tumor markers were normal; endocrinological findings indicated hypergonadotropic hypogonadism. Semen analyses revealed azoospermia. Preoperative chromosome test result: 47, XXY karyotype; ultrasonography report: 1.9-cm internal heterogeneous echoic mass in the right testis (malignancy not discarded). Because the patient hoped for children, he underwent high orchiectomy with ipsilateral testicular sperm extraction (200 spermatozoa from normal testicular tissue) for future fertilization procedures. Tumor pathology was an epidermal cyst.
While performing orchiectomy for testicular tumors, sperm retrieval should be attempted from normal tissues in patients planning for children.
克氏综合征患者出现睾丸表皮样囊肿极为罕见。我们报告一例克氏综合征合并睾丸表皮样囊肿的病例。据我们所知，这是首例显示从患侧睾丸成功获取精子的报告。
一名25岁已婚男性因右侧阴囊硬结被转诊至我院，硬结位于右侧睾丸下极。睾丸癌肿瘤标志物正常；内分泌检查结果提示高促性腺激素性性腺功能减退。精液分析显示无精子症。术前染色体检查结果：核型为47, XXY；超声检查报告：右侧睾丸内有一个1.9厘米的内部回声不均匀肿块（不能排除恶性）。由于患者希望生育，他接受了高位睾丸切除术并同时进行同侧睾丸取精（从正常睾丸组织中获取了200条精子），以备未来的受精程序。肿瘤病理检查为表皮样囊肿。
对于计划生育的患者，在进行睾丸肿瘤睾丸切除术时，应尝试从正常组织中获取精子。
