妊娠期肾细胞癌的治疗：提示肿瘤快速生长的组织病理学发现。
Renal cell carcinoma treatment during pregnancy: Histopathological findings suggestive of rapid tumor growth.
作者信息
Ohyama Takehiro, Shimbo Masaki, Endo Fumiyasu, Kyono Yoko, Akitani Fumi, Hayashi Tokuhito, Komatsu Kenji, Matsushita Kazuhito, Suzuki Kosuke, Hattori Kazunori
机构信息
Department of Urology St. Luke's International Hospital Tokyo Japan.
Department of Gynecology St. Luke's International Hospital Tokyo Japan.
出版信息
IJU Case Rep. 2019 Jun 19;2(5):265-268. doi: 10.1002/iju5.12098. eCollection 2019 Sep.
INTRODUCTION
Diagnosis of renal cell carcinoma during pregnancy is rare. We report a case of renal cell carcinoma during pregnancy with rapid growth.
CASE PRESENTATION
A 39-year-old woman presented to our hospital for treatment of renal tumor at 22 weeks gestation. The tumor had a cystic lesion with a partition and showed rapid growth from 28 mm to 32 mm over a period of 4 weeks. The tumor was diagnosed as renal cell carcinoma and an open partial nephrectomy was scheduled at 26 weeks gestation. The operation and perioperative course were successful. Pathological findings confirmed the tumor to be clear cell renal cell carcinoma with G2 > G3, Fuhrman grade 2, pT1a, negative surgical margin, and positive detection of progesterone receptor.
CONCLUSION
We reported the successful management of a patient who was diagnosed with renal cell carcinoma during pregnancy. We also had a suggested association between rapid growth tumor and progesterone based on histopathological analysis of the tumor.
引言
孕期诊断出肾细胞癌很罕见。我们报告一例孕期肾细胞癌且肿瘤生长迅速的病例。
病例介绍
一名39岁女性在妊娠22周时因肾肿瘤到我院就诊。肿瘤有一个带分隔的囊性病变，在4周内从28毫米迅速生长到32毫米。该肿瘤被诊断为肾细胞癌，并计划在妊娠26周时进行开放性部分肾切除术。手术及围手术期过程顺利。病理结果证实肿瘤为透明细胞肾细胞癌，G2＞G3，福尔曼分级2级，pT1a，手术切缘阴性，孕激素受体检测呈阳性。
结论
我们报告了一名孕期被诊断为肾细胞癌患者的成功治疗。基于对肿瘤的组织病理学分析，我们还提出了肿瘤快速生长与孕激素之间的关联。
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