Watanabe Keitaro, Shirotake Suguru, Umezawa Yuta, Takahashi Takayuki, Yamanaka Takeshi, L Santo Noriaki, Okabe Takashi, Kaneko Gou, Sano Katsuhiro, Yasuda Masanori, Kanao Kent, Oyama Masafumi, Nishimoto Koshiro
Department of Uro-Oncology Saitama Medical University International Medical Center Saitama Japan.
Department of Diagnostic Radiology Saitama Medical University International Medical Center Saitama Japan.
IJU Case Rep. 2019 Sep 13;2(6):313-316. doi: 10.1002/iju5.12109. eCollection 2019 Nov.
Transurethral resection of bladder tumor is widely used in combination with photodynamic diagnosis to treat non-muscle invasive bladder cancer. We experienced an intriguing case, in which bladder cancer infiltrated into the right ureteral orifice and was resected via photodynamic diagnosis-assisted transurethral resection involving the oral administration of 5-aminolevulinic acid.
This case was a 71-year-old Japanese man. He was diagnosed with bladder carcinoma, which had infiltrated into the right ureter (clinical classification: T1, N0, M0). He underwent transurethral resection involving the oral administration of 5-aminolevulinic acid. We successfully resected the tumor in the ureteral orifice, which was accomplished by resecting the ureteral orifice until the non-luminescent lumen was exposed. After the surgery, to prevent recurrence, Bacillus Calmette-Guérin was administered intravesically after right ureteral stent placement.
Photodynamic diagnosis-assisted transurethral resection involving the oral administration of 5-aminolevulinic acid has the potential to treat ureteral tumors derived from bladder tumors.
经尿道膀胱肿瘤切除术广泛应用于联合光动力诊断治疗非肌层浸润性膀胱癌。我们遇到了一个有趣的病例，其中膀胱癌浸润至右侧输尿管口，并通过口服5-氨基酮戊酸的光动力诊断辅助经尿道切除术进行了切除。
该病例为一名71岁的日本男性。他被诊断患有浸润至右侧输尿管的膀胱癌（临床分期：T1，N0，M0）。他接受了口服5-氨基酮戊酸的经尿道切除术。我们成功切除了输尿管口的肿瘤，方法是切除输尿管口直至暴露无荧光的管腔。术后，为防止复发，在右侧输尿管支架置入后膀胱内灌注卡介苗。
口服5-氨基酮戊酸的光动力诊断辅助经尿道切除术有治疗源自膀胱肿瘤的输尿管肿瘤的潜力。
