胃肠病学家主导的炎症性肠病缺铁性贫血管理有效、安全且可能提高生活质量。
Gastroenterologist-Lead Management of Iron Deficiency Anemia in Inflammatory Bowel Disease Is Effective, Safe, and May Increase Quality of Life.
作者信息
Coe Christopher L, Meyers Matthew H, Beaulieu Dawn B, Scoville Elizabeth, Schwartz David A, Horst Sara N, Dalal Robin L
机构信息
Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine and Public Health, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
出版信息
Crohns Colitis 360. 2020 Jul;2(3):otaa051. doi: 10.1093/crocol/otaa051. Epub 2020 Jun 24.
Abstract
BACKGROUND
The effectiveness and safety of gastroenterologist (GI)-lead treatment of iron deficiency anemia (IDA) in inflammatory bowel disease (IBD) have not been well-studied.
METHODS
A retrospective chart review of patients with IBD, IDA, and evidence of treatment with iron at a tertiary IBD center was conducted.
RESULTS
In 351 patients, hemoglobin and quality of life scores increased significantly after treatment with iron. Twelve of 341 patients treated with intravenous iron had an adverse effect. Twenty-seven patients required a hematology referral.
CONCLUSION
GIs should consider treating patients with IBD and IDA with intravenous iron as it is safe and effective.
摘要
背景
炎症性肠病（IBD）患者缺铁性贫血（IDA）由胃肠病学家主导治疗的有效性和安全性尚未得到充分研究。
方法
对一家三级IBD中心患有IBD、IDA且有铁剂治疗证据的患者进行回顾性病历审查。
结果
351例患者经铁剂治疗后血红蛋白和生活质量评分显著提高。341例接受静脉铁剂治疗的患者中有12例出现不良反应。27例患者需要血液科会诊。
结论
胃肠病学家应考虑对IBD和IDA患者采用静脉铁剂治疗，因为它安全有效。
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