基于全国健康和营养调查的中风风险因素。
Risk Factors for Stroke Based on the National Health and Nutrition Examination Survey.
机构信息
Xingmin Liang: Department of Emergency, Panyu Central Hospital, Guangzhou, Guangdong 510006, P.R. China, Tel: +86 020-3485800, E-mail:
出版信息
J Nutr Health Aging. 2020;24(7):791-795. doi: 10.1007/s12603-020-1430-4.
OBJECTIVES
To explore the risk factors for stroke by using National Health and Nutrition Examination Survey (NHANES).
METHODS
A total of 19384 cases from the NHANES database during 2005 to 2016 were included in this study, of which 661 were stroke patients, with a weighted prevalence of 2.60%. Univariate and multivariate logistic regression analysis was used to analyze possible risk factors for stroke.
RESULTS
The risk of stroke was 1.839 times higher in subjects with diabetes than in those without diabetes, P<0.001. An average increase of 1 ug/dL in blood lead was associated with a 1.082-fold increase in stroke risk, P<0.001. Subjects with mild-, moderate-, and moderately severe or severe depression had a 1.567-fold, 1.836-fold, and 3.279-fold higher risk than those without depression respectively, P<0.001. The risk of stroke in subjects with sleep disorders was 1.622 times higher than those without sleep disorders, P<0.001.
CONCLUSIONS
Patients with diabetes, lower household income (<$2000), PHQ-9 depression score (5-27), trouble sleep, older age and higher concentration of blood lead are associated with a higher risk of stroke.
目的
利用国家健康与营养调查（NHANES）探讨卒中的危险因素。
方法
本研究纳入了 2005 年至 2016 年 NHANES 数据库中的 19384 例患者，其中 661 例为卒中患者，加权患病率为 2.60%。采用单因素和多因素 logistic 回归分析方法分析卒中的可能危险因素。
结果
与无糖尿病者相比，糖尿病患者卒中风险增加 1.839 倍，P<0.001。血铅平均每增加 1μg/dL，卒中风险增加 1.082 倍，P<0.001。轻度、中度、中重度或重度抑郁者卒中风险分别是无抑郁者的 1.567 倍、1.836 倍和 3.279 倍，P<0.001。睡眠障碍者卒中风险比无睡眠障碍者高 1.622 倍，P<0.001。
结论
糖尿病、家庭收入较低（<$2000）、PHQ-9 抑郁评分（5-27）、睡眠障碍、年龄较大和血铅浓度较高与卒中风险增加相关。
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