Division of Nephrology, University of Toronto, 200 Elizabeth Street, 8N room 846, Toronto, ON, M5G 2C4, Canada.
University Health Network, Toronto, Canada.
BMC Nephrol. 2020 Aug 3;21(1):322. doi: 10.1186/s12882-020-01977-5.
Patients with End-Stage Renal Disease (ESRD) are at an increased risk for restrictive lung disease due to accumulation of uremic toxins and volume overload. Hemodialysis is the preferred treatment for improving lung function in dialysis patients. However, the effects of fluid removal and solute clearance by hemodialysis on lung function remain unclear.
We report a case of restrictive lung disorder in a hemodialysis patient, who showed improvement in both clinical and spirometric lung function after initiation of intensive home hemodialysis (32 h per week).
Intensive hemodialysis augments fluid removal and solute clearance, which in turn may improve restrictive lung function.
终末期肾病（ESRD）患者由于尿毒症毒素蓄积和容量超负荷而患限制性肺病的风险增加。血液透析是改善透析患者肺功能的首选治疗方法。然而，血液透析清除液体和溶质对肺功能的影响尚不清楚。
我们报告了一例血液透析患者的限制性肺疾病，该患者在开始强化家庭血液透析（每周 32 小时）后，临床和肺功能的限制性均得到改善。
强化血液透析可增加液体清除和溶质清除，从而可能改善限制性肺功能。
