Center for Applied Research on Substance Use and Health Disparities, Nova Southeastern University, Miami, FL, USA.
J Psychoactive Drugs. 2021 Jan-Mar;53(1):47-54. doi: 10.1080/02791072.2020.1802087. Epub 2020 Aug 4.
Gabapentin has received increased attention due to a growing number of reports of misuse and diversion. However, significant details about gabapentin misuse are scant. Data are drawn from a mixed-methods study examining gabapentin misuse in South Florida. The sample includes 49 respondents who were age 18 or over and reported past year use of illicit opioids and/or the misuse of prescription opioid medications, as well as, recent (past 90 days) gabapentin misuse. Respondents were female (40.8%), Hispanic (30.6%), Black (16.3%), white (49.0%), and other race/ethnicity (4.1%). Mean age was 37.6. Many respondents (43%) misused gabapentin without ever receiving a prescription and 14% misused prior to being prescribed. Mean frequency of recent misuse was 25.4 days and included a mean of 51.65 pills/doses. Prevalent routes of administration included swallowing (85.7%) and snorting (10.2%). Gabapentin misuse occurred concomitantly with any opioid (44.9%), benzodiazepines (38.8%), alcohol (24.5%), and powder cocaine (24.5), among others. Respondents' descriptions indicate that gabapentin produces feelings reminiscent of alcohol intoxication or opioid-induced euphoria, but for some it produces no noticeable effect or only alleviates pain. Greater understanding of gabapentin misuse, especially associated behaviors and concomitant use is needed to inform prevention and intervention efforts, and to guide policy approaches.
加巴喷丁由于越来越多的误用和转用报告而受到更多关注。然而,关于加巴喷丁滥用的详细信息却很少。这些数据来自一项混合方法研究,该研究调查了南佛罗里达州的加巴喷丁滥用情况。该样本包括 49 名年龄在 18 岁或以上的受访者,他们报告过去一年曾使用过非法阿片类药物和/或处方阿片类药物滥用,以及最近(过去 90 天)滥用加巴喷丁。受访者中女性占 40.8%,西班牙裔占 30.6%,黑人占 16.3%,白人占 49.0%,其他种族/族裔占 4.1%。平均年龄为 37.6 岁。许多受访者(43%)在没有处方的情况下滥用加巴喷丁,14%在开处方前就滥用了。最近滥用的平均频率为 25.4 天,平均剂量为 51.65 片/剂。常见的给药途径包括口服(85.7%)和鼻吸(10.2%)。加巴喷丁滥用与任何阿片类药物(44.9%)、苯二氮䓬类药物(38.8%)、酒精(24.5%)和粉末可卡因(24.5%)等同时发生。受访者的描述表明,加巴喷丁会产生类似于酒精中毒或阿片类药物引起的欣快感的感觉,但对一些人来说,它没有产生明显的效果,或者只是缓解疼痛。为了更好地了解加巴喷丁滥用情况,尤其是相关行为和同时使用情况,有必要开展预防和干预工作,并为政策方法提供指导。