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在治疗和康复环境中对加巴喷丁滥用的定性研究。

A Qualitative Examination of Gabapentin Misuse Inside of Treatment and Recovery Settings.

机构信息

Center for Applied Research on Substance Use and Health Disparities, Nova Southeastern University, Miami, Florida.

出版信息

J Stud Alcohol Drugs. 2020 Sep;81(5):681-686. doi: 10.15288/jsad.2020.81.681.

Abstract

OBJECTIVE

Gabapentin, an anti-convulsant medication used to treat seizures and neuralgia, is also prescribed off-label for the treatment of substance use disorders and withdrawal symptoms in treatment settings. Yet, reports of gabapentin misuse are increasing in the United States. The present study examines the misuse of gabapentin in treatment and transitional living facility settings.

METHOD

Data are drawn from a study examining gabapentin misuse in South Florida. The sample includes 34 adult participants who reported past-year use of illicit opioids and/or the misuse of prescription opioid medications, as well as histories of gabapentin misuse and treatment for substance use disorder. Data analyses included descriptive and in vivo coding schemes and used a descriptive qualitative approach.

RESULTS

Participants were female (26.5%), White (67.6%), African American/Black (5.9%), Hispanic (20.6%), Asian (2.9%), and other race/ethnicity (2.9%). Mean age was 31.6 years. Findings indicate that inside of treatment and recovery settings, gabapentin misuse occurs as individuals attempt to get high or cope with withdrawal or mental distress symptoms, and one quarter of participants perceived no benefit in misusing gabapentin. Participants also described the concept of "freelapse" (i.e., justifying the misuse of prescribed gabapentin and still considering oneself to be sober). Gabapentin misuse inside of transitional living facilities is common because of limited supervision and screening.

CONCLUSIONS

Continued research is needed to understand the risk factors for gabapentin misuse and any potential benefits for continued gabapentin administration among treatment patients. Efforts to mitigate gabapentin misuse, including increased supervision and screening in treatment facilities, appear warranted.

摘要

目的

加巴喷丁是一种用于治疗癫痫和神经痛的抗惊厥药物,也被开处方用于治疗物质使用障碍和治疗环境中的戒断症状。然而,在美国,加巴喷丁滥用的报告正在增加。本研究检查了治疗和过渡生活设施环境中加巴喷丁的滥用情况。

方法

数据来自一项在南佛罗里达州研究加巴喷丁滥用情况的研究。该样本包括 34 名报告过去一年滥用非法阿片类药物和/或处方类阿片药物滥用以及加巴喷丁滥用和物质使用障碍治疗史的成年参与者。数据分析包括描述性和现场编码方案,并使用描述性定性方法。

结果

参与者为女性(26.5%)、白人(67.6%)、非裔美国人/黑人(5.9%)、西班牙裔(20.6%)、亚洲人(2.9%)和其他种族/民族(2.9%)。平均年龄为 31.6 岁。研究结果表明,在治疗和康复环境中,加巴喷丁的滥用是因为个人试图获得快感或应对戒断或精神困扰症状,四分之一的参与者认为滥用加巴喷丁没有好处。参与者还描述了“自由复吸”的概念(即,为处方加巴喷丁的滥用辩护,并仍然认为自己是清醒的)。由于监管和筛查有限,过渡生活设施中加巴喷丁的滥用很常见。

结论

需要进一步研究以了解加巴喷丁滥用的风险因素以及治疗患者中继续使用加巴喷丁的任何潜在益处。加强监管和筛查,以减少加巴喷丁的滥用,似乎是必要的。

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Gabapentin: can it be misused?加巴喷丁:它会被滥用吗?
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Misuse of prescribed opioids in the United States.美国处方类阿片的滥用
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