Department of Orthopaedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.
Nursing Department, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.
J Fluoresc. 2020 Sep;30(5):1225-1232. doi: 10.1007/s10895-020-02598-9. Epub 2020 Aug 4.
A novel coordination polymer (CP) based on Zn(II) of [Zn(tptc)(bpy)(HO)] (1) was synthesized through utilizing the 2,2'-bipyridine (bpy) chelating N donors and p-terphenyl-2,2'',5'',5'''-tetracarboxylate acid (Htptc) as the co-ligands. The measurements of the fluorescence were implemented for the complex 1 in solution and solid state, and the result reveals that 1 has a strong fluorescence and it is a sensory material with great development space to determine the trace CrO (with the detection limit of 36 ppb) in the water solutions via applying the fluorescence quenching effect. As the common disease in the orthopedic nursing, the deep vein thrombosis was the objective in this research. The weigh and length of the thrombus in the animals were measured and analyzed. In addition to this, the inflammatory response in the deep vein thrombosis animal was evaluated by RT-PCR. Molecular docking results indicate that only the carboxyl group could provide polar oxygen atoms for the formed hydrogen bonds to the protein.
一种基于 Zn(II)的新型配位聚合物 (CP) [Zn(tptc)(bpy)(HO)]（1）通过利用 2,2'-联吡啶 (bpy) 螯合 N 供体和对三联苯-2,2'',5'',5'''-四羧酸 (Htptc) 作为共配体合成。对配合物 1 在溶液和固态中的荧光进行了测量，结果表明 1 具有很强的荧光，并且是一种具有很大发展空间的感测材料，可以通过应用荧光猝灭效应来确定水溶液中的痕量 CrO（检测限为 36 ppb）。深静脉血栓形成是骨科护理中的常见疾病，也是本研究的对象。测量和分析了动物体内血栓的重量和长度。此外，通过 RT-PCR 评估了深静脉血栓形成动物的炎症反应。分子对接结果表明，只有羧基才能为形成的氢键提供极性氧原子与蛋白质结合。
