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[甲状腺功能减退和腮腺切除大鼠皮肤伤口肉芽组织中肥大细胞群体变化的形态计量学测定]

[Morphometric determination of changes in mastocyte population in cutaneous wound granulation tissue in hypothyroid and parotidectomized rats].

作者信息

Vieira T M, Matheus G

出版信息

Arq Cent Estud Curso Odontol. 1988;25-26(1-2):22-7.

PMID:3275170
Abstract

The authors have done a morphometric study by determination of mastocyte population of cutaneous wound's granulation tissue of parotidectomized rats and rats which were submitted to daily administration of 25 mg of 6-propyl-2-thiouracil (hypothyroid). The animals were sacrificed after four, eight and 12 post-operative days. The results analysis permitted to observe a statistically significant diminution of mastocyte population in the hypothyroid and parotidectomized animals granulation tissue in the fourth and 12th postsurgical days.

摘要

作者通过测定腮腺切除大鼠以及每日给予25毫克6-丙基-2-硫氧嘧啶(甲状腺功能减退)的大鼠皮肤伤口肉芽组织中的肥大细胞数量,进行了一项形态计量学研究。在术后第4、8和12天处死动物。结果分析显示,在术后第4天和第12天,甲状腺功能减退和腮腺切除动物的肉芽组织中肥大细胞数量有统计学意义的减少。

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