Clinical Trials Unit, University of Warwick, Coventry, UK
Trauma and Orthopaedics, --University Hospital Coventry and Warwickshire, Coventry, West Midlands, UK.
BMJ Open. 2020 Aug 4;10(8):e036247. doi: 10.1136/bmjopen-2019-036247.
Meniscal tears are a common knee injury with an incidence of 60 per 100 000. Management of meniscal tears can include either non-operative measures or operative procedures such as arthroscopic partial meniscectomy (APM). Despite substantial research evaluating the effectiveness of APM in the recent past, little is known about the clinical course or the experiences of patients with a meniscal tear.
To summarise the short to long-term patterns of variability in outcome in patients with a meniscal tear.To summarise the evidence on patient experiences of meniscal tears. In particular, we will focus on patient experiences of treatment options, treatment pathways and their views of the outcomes used in meniscal tear research.
Two search strategies will be developed to identify citations from EMBASE, MEDLINE, AMED, CENTRAL, Web of Science and Sociofile. The date of our planned search is 14 August 2020. For the quantitative review we will identify studies reporting patient-reported outcome measures in patients after a meniscal tear. The standardised mean change will be used to assess the variation in size of response and summarise the overall response to each treatment option. All studies will undergo quality assessment using either the Cochrane risk of bias or the Newcastle-Ottawa tool.A qualitative systematic review will be used to identify studies reporting views and experiences of patients with a meniscal tear. All studies will be assessed using the Critical Appraisal Skills Programme tool and if sufficient data are present a meta-synthesis will be performed to identify first, second and third-order constructs.
Given the nature of this study, no formal ethical approval will be sought. Results from the review will be disseminated at national conferences and will be submitted to a peer-reviewed journal for publication. Lay summaries will be freely available via the study Twitter page.
CRD42019122179.
半月板撕裂是一种常见的膝关节损伤,发病率为每 10 万人中有 60 人。半月板撕裂的治疗方法包括非手术治疗或手术治疗,如关节镜下部分半月板切除术(APM)。尽管最近有大量研究评估了 APM 的有效性,但对于半月板撕裂患者的临床过程或体验知之甚少。
总结半月板撕裂患者短期至长期结局变化的模式。总结半月板撕裂患者体验的证据。特别是,我们将重点关注患者对治疗选择、治疗途径的体验以及他们对半月板撕裂研究中使用的结局的看法。
将制定两种检索策略,以从 EMBASE、MEDLINE、AMED、CENTRAL、Web of Science 和 Sociofile 中识别引文。我们计划的检索日期是 2020 年 8 月 14 日。对于定量综述,我们将确定报告半月板撕裂后患者报告的结局测量指标的研究。将使用标准化均数差值来评估反应大小的变化,并总结每种治疗选择的总体反应。所有研究都将使用 Cochrane 偏倚风险或 Newcastle-Ottawa 工具进行质量评估。定性系统综述将用于确定报告半月板撕裂患者观点和体验的研究。所有研究都将使用关键评估技能计划工具进行评估,如果有足够的数据,将进行元综合分析,以确定第一、第二和第三级结构。
鉴于本研究的性质,将不寻求正式的伦理批准。审查结果将在全国会议上公布,并提交给同行评议期刊发表。通俗易懂的摘要将通过研究的 Twitter 页面免费提供。
PROSPERO 注册号:CRD42019122179。