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人乳铁蛋白的杀菌作用。

A bactericidal effect for human lactoferrin.

作者信息

Arnold R R, Cole M F, McGhee J R

出版信息

Science. 1977 Jul 15;197(4300):263-5. doi: 10.1126/science.327545.

DOI:10.1126/science.327545
PMID:327545
Abstract

Streptococcus mutans and Vibrio cholerae, but not Escherichia coli, were killed by incubation with purified human apolactoferrin. Concentrations of lactoferrin below that necessary for total inhibition resulted in a marked reduction in viable colony-forming units. This bactericidal effect was contingent upon the metal-chelating properties of the lactoferrin molecule.

摘要

变形链球菌和霍乱弧菌,而非大肠杆菌,经与纯化的人脱铁乳铁蛋白孵育后被杀死。低于完全抑制所需浓度的乳铁蛋白会导致活菌形成单位显著减少。这种杀菌作用取决于乳铁蛋白分子的金属螯合特性。

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