人乳铁蛋白的杀菌作用。
A bactericidal effect for human lactoferrin.
作者信息
Arnold R R, Cole M F, McGhee J R
出版信息
Science. 1977 Jul 15;197(4300):263-5. doi: 10.1126/science.327545.
PMID:327545
Abstract
Streptococcus mutans and Vibrio cholerae, but not Escherichia coli, were killed by incubation with purified human apolactoferrin. Concentrations of lactoferrin below that necessary for total inhibition resulted in a marked reduction in viable colony-forming units. This bactericidal effect was contingent upon the metal-chelating properties of the lactoferrin molecule.
摘要
变形链球菌和霍乱弧菌，而非大肠杆菌，经与纯化的人脱铁乳铁蛋白孵育后被杀死。低于完全抑制所需浓度的乳铁蛋白会导致活菌形成单位显著减少。这种杀菌作用取决于乳铁蛋白分子的金属螯合特性。
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