• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Demystifying pulmonary fibrosis.揭开肺纤维化的神秘面纱。
Am J Physiol Lung Cell Mol Physiol. 2020 Sep 1;319(3):L554-L559. doi: 10.1152/ajplung.00365.2020. Epub 2020 Aug 5.
2
Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling.特发性肺纤维化中过氧化物酶体受损，这是一个通过转化生长因子-β信号传导诱导更高纤维化反应的恶性循环。
Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E2048-57. doi: 10.1073/pnas.1415111112. Epub 2015 Apr 6.
3
[The expressions and meanings of BMP-7 and TGF-β in idiopathic pulmonary fibrosis and idiopathic nonspecific interstitial pneumonia].[骨形态发生蛋白-7和转化生长因子-β在特发性肺纤维化和特发性非特异性间质性肺炎中的表达及意义]
Zhonghua Jie He He Hu Xi Za Zhi. 2014 Sep;37(9):664-70.
4
USP7 Promotes TGF-β1 Signaling by De-Ubiquitinating Smad2/Smad3 in Pulmonary Fibrosis.USP7 通过去泛素化 Smad2/Smad3 促进肺纤维化中的 TGF-β1 信号传导。
Discov Med. 2024 Aug;36(187):1616-1626. doi: 10.24976/Discov.Med.202436187.148.
5
13-Methylpalmatine alleviates bleomycin-induced pulmonary fibrosis by suppressing the ITGA5/TGF-β/Smad signaling pathway.13-甲基巴马汀通过抑制整合素α5/转化生长因子-β/信号转导和转录激活因子信号通路减轻博来霉素诱导的肺纤维化。
Phytomedicine. 2025 May;140:156545. doi: 10.1016/j.phymed.2025.156545. Epub 2025 Mar 1.
6
The Role of TGF-β Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis.TGF-β 信号通路在特发性肺纤维化相关肺癌中的作用。
Int J Mol Sci. 2018 Nov 15;19(11):3611. doi: 10.3390/ijms19113611.
7
SULF1 expression is increased and promotes fibrosis through the TGF-β1/SMAD pathway in idiopathic pulmonary fibrosis.在特发性肺纤维化中，SULF1表达增加并通过TGF-β1/SMAD途径促进纤维化。
J Transl Med. 2024 Oct 1;22(1):885. doi: 10.1186/s12967-024-05698-3.
8
Comparative study of transforming growth factor-β signalling and regulatory molecules in human and canine idiopathic pulmonary fibrosis.人类和犬特发性肺纤维化中转化生长因子-β信号传导与调节分子的比较研究
J Comp Pathol. 2014 May;150(4):399-407. doi: 10.1016/j.jcpa.2013.12.001. Epub 2013 Dec 10.
9
Profibrotic role of WNT10A via TGF-β signaling in idiopathic pulmonary fibrosis.WNT10A通过转化生长因子-β信号通路在特发性肺纤维化中的促纤维化作用。
Respir Res. 2016 Apr 12;17:39. doi: 10.1186/s12931-016-0357-0.
10
The soluble factor milieu in idiopathic pulmonary fibrosis dysregulates epithelial differentiation.特发性肺纤维化中可溶性因子微环境失调上皮细胞分化。
FASEB J. 2024 Oct 15;38(19):e70077. doi: 10.1096/fj.202302405RR.

引用本文的文献

1
CompCorona: A web application for comparative transcriptome analyses of coronaviruses reveals SARS-CoV-2-specific host response.CompCorona：一款用于冠状病毒比较转录组分析的网络应用程序揭示了新冠病毒特异性宿主反应。
Turk J Biol. 2023 Dec 15;47(6):393-405. doi: 10.55730/1300-0152.2673. eCollection 2023.
2
Longitudinal x-ray based lung function measurement for monitoring Nintedanib treatment response in a mouse model of lung fibrosis.基于 X 射线的纵向肺功能测量用于监测肺纤维化小鼠模型中尼达尼布的治疗反应。
Sci Rep. 2023 Oct 30;13(1):18637. doi: 10.1038/s41598-023-45305-x.
3
Targeting ATP12A, a Nongastric Proton Pump α Subunit, for Idiopathic Pulmonary Fibrosis Treatment.针对非胃质子泵α亚单位 ATP12A 治疗特发性肺纤维化。
Am J Respir Cell Mol Biol. 2023 Jun;68(6):638-650. doi: 10.1165/rcmb.2022-0264OC.
4
What role for asbestos in idiopathic pulmonary fibrosis? Findings from the IPF job exposures case-control study.石棉在特发性肺纤维化中的作用？IPF 职业暴露病例对照研究的结果。
Occup Environ Med. 2023 Feb;80(2):97-103. doi: 10.1136/oemed-2022-108404. Epub 2023 Jan 12.
5
The Interaction Between Pulmonary Fibrosis and COVID-19 and the Application of Related Anti-Fibrotic Drugs.肺纤维化与新型冠状病毒肺炎的相互作用及相关抗纤维化药物的应用
Front Pharmacol. 2022 Jan 5;12:805535. doi: 10.3389/fphar.2021.805535. eCollection 2021.
6
From ARDS to pulmonary fibrosis: the next phase of the COVID-19 pandemic?从急性呼吸窘迫综合征到肺纤维化：COVID-19 大流行的下一阶段？
Transl Res. 2022 Mar;241:13-24. doi: 10.1016/j.trsl.2021.09.001. Epub 2021 Sep 20.
7
Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity.慢性肺部疾病与有利于 SARS-CoV-2 进入和严重程度的基因表达程序有关。
Nat Commun. 2021 Jul 14;12(1):4314. doi: 10.1038/s41467-021-24467-0.
8
Age-Related Dynamics of Lung-Resident Memory CD8 T Cells in the Age of COVID-19.新冠肺炎时代肺驻留记忆 CD8+T 细胞的年龄相关性动态变化。
Front Immunol. 2021 Mar 29;12:636118. doi: 10.3389/fimmu.2021.636118. eCollection 2021.
9
Shared genetic etiology between idiopathic pulmonary fibrosis and COVID-19 severity.特发性肺纤维化和 COVID-19 严重程度之间存在共享的遗传病因。
EBioMedicine. 2021 Mar;65:103277. doi: 10.1016/j.ebiom.2021.103277. Epub 2021 Mar 10.
10
Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity.慢性肺部疾病与有利于严重急性呼吸综合征冠状病毒2（SARS-CoV-2）进入和加重病情的基因表达程序相关。
bioRxiv. 2021 Jan 4:2020.10.20.347187. doi: 10.1101/2020.10.20.347187.

本文引用的文献

1
Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis.鉴定与特发性肺纤维化相关的 SPDL1 错义变异。
Commun Biol. 2021 Mar 23;4(1):392. doi: 10.1038/s42003-021-01910-y.
2
Metformin and risk of mortality in patients hospitalised with COVID-19: a retrospective cohort analysis.二甲双胍治疗 COVID-19 住院患者的死亡率风险：一项回顾性队列分析。
Lancet Healthy Longev. 2021 Jan;2(1):e34-e41. doi: 10.1016/S2666-7568(20)30033-7. Epub 2020 Dec 3.
3
Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease. An International Multicenter Study.间质性肺疾病患者 COVID-19 住院治疗结局。一项国际多中心研究。
Am J Respir Crit Care Med. 2020 Dec 15;202(12):1656-1665. doi: 10.1164/rccm.202007-2794OC.
4
Occupational and environmental risk factors for idiopathic pulmonary fibrosis in Australia: case-control study.澳大利亚特发性肺纤维化的职业和环境风险因素：病例对照研究。
Thorax. 2020 Oct;75(10):864-869. doi: 10.1136/thoraxjnl-2019-214478. Epub 2020 Jul 13.
5
Metformin Treatment Was Associated with Decreased Mortality in COVID-19 Patients with Diabetes in a Retrospective Analysis.回顾性分析显示，二甲双胍治疗与 COVID-19 合并糖尿病患者的死亡率降低相关。
Am J Trop Med Hyg. 2020 Jul;103(1):69-72. doi: 10.4269/ajtmh.20-0375. Epub 2020 May 21.
6
Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study.使用 ISARIC WHO 临床特征协议住院的 20133 例英国新冠患者的特征：前瞻性观察队列研究。
BMJ. 2020 May 22;369:m1985. doi: 10.1136/bmj.m1985.
7
Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy.肺纤维化与 COVID-19：抗纤维化治疗的潜在作用。
Lancet Respir Med. 2020 Aug;8(8):807-815. doi: 10.1016/S2213-2600(20)30225-3. Epub 2020 May 15.
8
Remdesivir in covid-19.瑞德西韦用于治疗新冠病毒肺炎
BMJ. 2020 Apr 22;369:m1610. doi: 10.1136/bmj.m1610.
9
A potential role for integrins in host cell entry by SARS-CoV-2.整合素在 SARS-CoV-2 进入宿主细胞中的潜在作用。
Antiviral Res. 2020 May;177:104759. doi: 10.1016/j.antiviral.2020.104759. Epub 2020 Mar 1.
10
Interstitial Lung Disease in Relatives of Patients with Pulmonary Fibrosis.肺纤维化患者亲属中的间质性肺病。
Am J Respir Crit Care Med. 2020 May 15;201(10):1240-1248. doi: 10.1164/rccm.201908-1571OC.

Demystifying pulmonary fibrosis.

作者信息

Jenkins Gisli

机构信息

National Institute for Health Research, Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom.

出版信息

Am J Physiol Lung Cell Mol Physiol. 2020 Sep 1;319(3):L554-L559. doi: 10.1152/ajplung.00365.2020. Epub 2020 Aug 5.

DOI:10.1152/ajplung.00365.2020
PMID:32755321
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7839634/
Abstract
摘要