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2
TIPICO IX: report of the 9 interactive infectious disease workshop on infectious diseases and vaccines.特皮科九：传染病与疫苗第九次互动传染病研讨会报告。
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The effect of Bacillus Calmette-Guérin (BCG) vaccination in preventing severe infectious respiratory diseases other than TB: Implications for the COVID-19 pandemic.卡介苗（BCG）接种预防除结核病以外的严重传染性呼吸道疾病的效果：对 COVID-19 大流行的影响。
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Vaccine-preventable diseases and their impact on Latin American children.可预防疫苗疾病及其对拉丁美洲儿童的影响。
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A single, low dose of a cGMP recombinant BCG vaccine elicits protective T cell immunity against the human respiratory syncytial virus infection and prevents lung pathology in mice.单剂量低剂量的cGMP重组卡介苗可引发针对人类呼吸道合胞病毒感染的保护性T细胞免疫，并预防小鼠的肺部病变。
Vaccine. 2017 Feb 1;35(5):757-766. doi: 10.1016/j.vaccine.2016.12.048. Epub 2017 Jan 5.
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Immunomodulatory Effect of the Bacillus Calmette-Guérin (BCG) Vaccine on the Interferon Response Induced by Respiratory Syncytial Virus (RSV) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antigens.卡介苗（BCG）疫苗对呼吸道合胞病毒（RSV）和严重急性呼吸综合征冠状病毒2（SARS-CoV-2）抗原诱导的干扰素反应的免疫调节作用。
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Multiple BCG vaccinations for the prevention of COVID-19 and other infectious diseases in type 1 diabetes.多次接种卡介苗预防 1 型糖尿病患者感染 COVID-19 和其他传染病。
Cell Rep Med. 2022 Sep 20;3(9):100728. doi: 10.1016/j.xcrm.2022.100728. Epub 2022 Aug 15.
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Mycobacterium bovis BCG Given at Birth Followed by Inactivated Respiratory Syncytial Virus Vaccine Prevents Vaccine-Enhanced Disease by Promoting Trained Macrophages and Resident Memory T Cells.牛分枝杆菌卡介苗在出生时接种，随后接种呼吸道合胞病毒灭活疫苗，可通过促进训练有素的巨噬细胞和固有记忆 T 细胞来预防疫苗增强疾病。
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A Recombinant BCG Vaccine Is Safe and Immunogenic in Neonatal Calves and Reduces the Clinical Disease Caused by the Respiratory Syncytial Virus.一种重组卡介苗疫苗在新生小牛中安全且具有免疫原性，并可降低呼吸道合胞病毒引起的临床疾病。
Front Immunol. 2021 Apr 26;12:664212. doi: 10.3389/fimmu.2021.664212. eCollection 2021.

本文引用的文献

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Zoonoses Anticipation and Preparedness Initiative, stakeholders conference, February 4 & 5, 2021.动物源传染病防范与应对倡议利益攸关方会议，2021 年 2 月 4 日和 5 日。
Biologicals. 2021 Nov;74:10-15. doi: 10.1016/j.biologicals.2021.10.003. Epub 2021 Nov 1.
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The nasopharyngeal microbiome.鼻咽微生物群
Emerg Top Life Sci. 2017 Nov 30;1(4):297-312. doi: 10.1042/ETLS20170041.
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Success of 4CMenB in preventing meningococcal disease: evidence from real-world experience.4CMenB 在预防脑膜炎球菌病方面的成功：来自真实世界经验的证据。
Arch Dis Child. 2020 Aug;105(8):784-790. doi: 10.1136/archdischild-2019-318047. Epub 2020 Feb 6.
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Meningococcal B Vaccine and Meningococcal Carriage in Adolescents in Australia.在澳大利亚，青少年中的 B 型脑膜炎球菌疫苗和脑膜炎球菌带菌情况。
N Engl J Med. 2020 Jan 23;382(4):318-327. doi: 10.1056/NEJMoa1900236.
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Global burden of cancer attributable to infections in 2018: a worldwide incidence analysis.2018 年归因于感染的癌症全球负担：全球发病率分析。
Lancet Glob Health. 2020 Feb;8(2):e180-e190. doi: 10.1016/S2214-109X(19)30488-7. Epub 2019 Dec 17.
6
IgA and IgG1 Specific to Vi Polysaccharide of Typhi Correlate With Protection Status in a Typhoid Fever Controlled Human Infection Model.血清型 Vi 多糖的 IgA 和 IgG1 特异性与伤寒感染人体模型中的保护状态相关。
Front Immunol. 2019 Nov 1;10:2582. doi: 10.3389/fimmu.2019.02582. eCollection 2019.
7
Bacillus Calmette-Guérin (BCG) therapy lowers the incidence of Alzheimer's disease in bladder cancer patients.卡介苗（BCG）治疗可降低膀胱癌患者患阿尔茨海默病的发病率。
PLoS One. 2019 Nov 7;14(11):e0224433. doi: 10.1371/journal.pone.0224433. eCollection 2019.
8
Broadly protective human antibodies that target the active site of influenza virus neuraminidase.广谱保护性人源抗体靶向流感病毒神经氨酸酶的活性位点。
Science. 2019 Oct 25;366(6464):499-504. doi: 10.1126/science.aay0678.
9
Meningococcal Group B Vaccine For The Prevention Of Invasive Meningococcal Disease Caused By Serogroup B.用于预防B群脑膜炎球菌引起的侵袭性脑膜炎球菌病的B群脑膜炎球菌疫苗
Infect Drug Resist. 2019 Oct 9;12:3169-3188. doi: 10.2147/IDR.S159952. eCollection 2019.
10
Immunogenicity of chimeric haemagglutinin-based, universal influenza virus vaccine candidates: interim results of a randomised, placebo-controlled, phase 1 clinical trial.嵌合血凝素为基础的通用流感病毒疫苗候选物的免疫原性：一项随机、安慰剂对照、1 期临床试验的中期结果。
Lancet Infect Dis. 2020 Jan;20(1):80-91. doi: 10.1016/S1473-3099(19)30393-7. Epub 2019 Oct 17.

TIPICO X：第十届传染病与疫苗互动式传染病研讨会报告

TIPICO X: report of the 10th interactive infectious disease workshop on infectious diseases and vaccines.

作者信息

Rivero-Calle Irene, Gómez-Rial Jose, Bont Louis, Gessner Bradford D, Kohn Melvin, Dagan Ron, Payne Daniel C, Bruni Laia, Pollard Andrew J, García-Sastre Adolfo, Faustman Denise L, Osterhaus Albert, Butler Robb, Giménez Sánchez Francisco, Álvarez Francisco, Kaforou Myrsini, Bello Xabier, Martinón-Torres Federico

机构信息

Translational Paediatrics and Infectious Diseases, Department of Paediatrics, Hospital Clínico Universitario De Santiago De Compostela, Santiago De Compostela, Spain.

Genetics, Vaccines and Infections Research Group (GENVIP), Instituto De Investigación Sanitaria De Santiago, Universidad De Santiago De Compostela, Santiago De Compostela, Spain.

出版信息

Hum Vaccin Immunother. 2021 Mar 4;17(3):759-772. doi: 10.1080/21645515.2020.1788301. Epub 2020 Aug 5.

DOI:
10.1080/21645515.2020.1788301
PMID:32755474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7996078/
Abstract

TIPICO is an expert meeting and workshop that aims to provide the most recent evidence in the field of infectious diseases and vaccination. The 10th Interactive Infectious Disease TIPICO workshop took place in Santiago de Compostela, Spain, on November 21-22, 2019. Cutting-edge advances in vaccination against respiratory syncytial virus, , rotavirus, human papillomavirus, , influenza virus, and Typhi were discussed. Furthermore, heterologous vaccine effects were updated, including the use of Bacillus Calmette-Guérin (BCG) vaccine as potential treatment for type 1 diabetes. Finally, the workshop also included presentations and discussion on emergent virus and zoonoses, vaccine resilience, building and sustaining confidence in vaccination, approaches to vaccine decision-making, pros and cons of compulsory vaccination, the latest advances in decoding infectious diseases by RNA gene signatures, and the application of big data approaches.

摘要

TIPICO是一个专家会议和研讨会，旨在提供传染病和疫苗领域的最新证据。第十届互动式传染病TIPICO研讨会于2019年11月21日至22日在西班牙圣地亚哥-德孔波斯特拉举行。会上讨论了呼吸道合胞病毒、轮状病毒、人乳头瘤病毒、流感病毒和伤寒疫苗的前沿进展。此外，还更新了异源疫苗的效果，包括使用卡介苗作为1型糖尿病的潜在治疗方法。最后，研讨会还包括关于新兴病毒和人畜共患病、疫苗弹性、建立和维持对疫苗接种的信心、疫苗决策方法、强制接种疫苗的利弊、通过RNA基因特征解码传染病的最新进展以及大数据方法的应用的演讲和讨论。