Translational Paediatrics and Infectious Diseases, Department of Paediatrics, Hospital Clínico Universitario de Santiago de Compostela , Santiago de Compostela , Spain.
Genetics, Vaccines and Infections Research group (GENVIP), Instituto de Investigación Sanitaria de Santiago, Universidad de Santiago de Compostela , Santiago de Compostela , Spain.
Hum Vaccin Immunother. 2019;15(10):2405-2415. doi: 10.1080/21645515.2019.1609823. Epub 2019 Jun 3.
The Ninth Interactive Infectious Disease workshop TIPICO was held on November 22-23, 2018, in Santiago de Compostela, Spain. This 2-day academic experience addressed current and topical issues in the field of infectious diseases and vaccination. Summary findings of the meeting include: cervical cancer elimination will be possible in the future, thanks to the implementation of global vaccination action plans in combination with appropriate screening interventions. The introduction of appropriate immunization programs is key to maintain the success of current effective vaccines such as those against meningococcal disease or rotavirus infection. Additionally, reduced dose schedules might improve the efficiency of some vaccines (i.e., PCV13). New vaccines to improve current preventive alternatives are under development (e.g., against tuberculosis or influenza virus), while others to protect against infectious diseases with no current available vaccines (e.g., enterovirus, parechovirus and flaviviruses) need to be developed. Vaccinomics will be fundamental in this process, while infectomics will allow the application of precision medicine. Further research is also required to understand the impact of heterologous vaccine effects. Finally, vaccination requires education at all levels (individuals, community, healthcare professionals) to ensure its success by helping to overcome major barriers such as vaccine hesitancy and false contraindications.
第九届互动传染病研讨会 TIPICO 于 2018 年 11 月 22 日至 23 日在西班牙圣地亚哥德孔波斯特拉举行。这两天的学术会议探讨了传染病和疫苗接种领域当前的热门话题。会议的主要结论包括:由于全球疫苗接种行动计划与适当的筛查干预措施相结合,未来有可能消除宫颈癌。实施适当的免疫规划是维持目前有效疫苗(如脑膜炎球菌病或轮状病毒感染疫苗)成功的关键。此外,减少剂量方案可能会提高某些疫苗(如 PCV13)的效率。正在开发新的疫苗来改善当前的预防替代品(例如,针对结核病或流感病毒),而针对目前尚无可用疫苗的传染病(例如,肠道病毒、肠道病毒和黄病毒)的疫苗则需要开发。疫苗组学将是这一过程的基础,而感染组学将允许应用精准医学。还需要进一步研究以了解异源疫苗效果的影响。最后,疫苗接种需要在各个层面(个人、社区、医疗保健专业人员)进行教育,以帮助克服疫苗犹豫和虚假禁忌症等主要障碍,从而确保其成功。