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糖棕(扇叶树头榈)果实未成熟胚乳对2型糖尿病患者的降糖作用——一项病例研究

Anti-hyperglycemic effect of the immature endosperm of sugar palm (Borassus flabellifer) fruit on type 2 diabetes mellitus patients-a case study.

作者信息

Rahman Shaikh Shahinur, Yasmin Nilufar, Kamruzzaman Md, Islam Md Rezwanul, Karim Md Rezaul, Rouf Shakh Ma

机构信息

Department of Applied Nutrition and Food Technology, Islamic University, Kushtia, Bangladesh.

Department of Biotechnology and Genetic Engineering, Islamic University, Kushtia, Bangladesh.

出版信息

Diabetes Metab Syndr. 2020 Sep-Oct;14(5):1317-1322. doi: 10.1016/j.dsx.2020.06.055. Epub 2020 Jul 9.

Abstract

AIM

This study aimed to investigate the nutrient contents and the anti-hyperglycemic effect of the immature endosperm of sugar palm (IESP) (Borassus flabellifer L.) fruit on type-2 diabetes mellitus (T2DM) patients.

METHODS

This is a short type case study where patients (n = 30) with T2DM were randomly selected and fed IESP (100 mL) twice a day after a regular meal and continued this experiment up to 4th weeks.

RESULT

The mean fasting blood glucose (FBG) level was markedly reduced from 1st week (15.74 mmol/L) to 4th week (10.53 mmol/L) among the patients who had normal body mass index (18.5-24.9). Only 16.67% diabetic patients had irregular FBG levels where 10% were in the previous stages after finishing the experimental period, and exceptionally in the case of 6.67% diabetic patients, this therapeutic juice was unsuccessful because of their irregular intake of insulin. The IESP was more effective on female (p ≤ 0.001) patients than males (p ≤ 0.05).

CONCLUSION

The IESP could be considered as anti-hyperglycemic fruit, and this might be due to its nutrient contents, especially phytochemicals, fiber, sodium, potassium, copper, and zinc.

摘要

目的

本研究旨在调查糖棕(Borassus flabellifer L.)果实未成熟胚乳(IESP)对2型糖尿病(T2DM)患者的营养成分及降血糖作用。

方法

这是一项简短的病例研究,随机选取30例T2DM患者,在正餐之后每天两次喂食IESP(100毫升),并将该实验持续进行至第4周。

结果

体重指数正常(18.5 - 24.9)的患者中,平均空腹血糖(FBG)水平从第1周(15.74毫摩尔/升)至第4周(10.53毫摩尔/升)显著降低。实验期结束后,仅16.67%的糖尿病患者FBG水平不稳定,其中10%处于先前阶段,而在6.67%的糖尿病患者中,由于胰岛素摄入不规律,这种治疗性果汁未取得成效。IESP对女性(p≤0.001)患者的效果优于男性(p≤0.05)。

结论

IESP可被视为具有降血糖作用的水果,这可能归因于其营养成分,尤其是植物化学物质、纤维、钠、钾、铜和锌。

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