Yang Mai-Qing, Bai Lin-Lin, Wang Zhao, Huang Wen-Jing, Jiang Gui-Yang, Xu Hong-Tao
Department of Pathology, The First Hospital and College of Basic Medical Sciences, China Medical University, Shenyang.
Department of Pathology, Changyi People's Hospital, Changyi.
Medicine (Baltimore). 2020 Jul 31;99(31):e21531. doi: 10.1097/MD.0000000000021531.
Thymic carcinoma with adenoid cystic carcinoma-like features is a special subtype of thymic adenocarcinoma, and the occurrence of this condition is extremely rare. Herein, we report a case of primary thymic carcinoma with adenoid cystic carcinoma-like features in a young man.
A 38-year-old man had an incidental finding of space-occupying lesion in the anterior mediastinum during a routine health examination. The patient complained of occasional mild chest tightness during hot weather but had no obvious cough, sputum, chest pain, or fever. Contrast-enhanced computed tomography scan of the chest revealed a space-occupying lesion in the anterior mediastinum, which is likely benign.
The lesion was diagnosed as a primary thymic carcinoma with adenoid cystic carcinoma-like features.
The patient underwent thoracoscopic resection of left anterior mediastinal mass and enlarged resection of thymectomy and mediastinal fat in our hospital.
The postoperative course was uneventful.
The tissue characteristic of this tumor was extremely similar to that of adenoid cystic carcinoma. A precise pathological examination is extremely important to prevent misdiagnoses of the lesion as adenoid cystic carcinoma or other thymic tumors. Immunohistochemical staining is extremely useful for the pathological and differential diagnoses of this tumor.
具有腺样囊性癌样特征的胸腺癌是胸腺腺癌的一种特殊亚型，这种情况极为罕见。在此，我们报告一例年轻男性原发性具有腺样囊性癌样特征的胸腺癌病例。
一名38岁男性在常规健康检查中偶然发现前纵隔占位性病变。患者主诉在炎热天气时有偶尔的轻度胸闷，但无明显咳嗽、咳痰、胸痛或发热症状。胸部增强计算机断层扫描显示前纵隔有占位性病变，可能为良性。
该病变被诊断为具有腺样囊性癌样特征的原发性胸腺癌。
患者在我院接受了胸腔镜下左前纵隔肿物切除术及扩大胸腺切除术和纵隔脂肪切除术。
术后过程顺利。
该肿瘤的组织特征与腺样囊性癌极为相似。进行精确的病理检查对于防止将该病变误诊为腺样囊性癌或其他胸腺肿瘤极为重要。免疫组织化学染色对该肿瘤的病理诊断和鉴别诊断极为有用。
