37663 School of Medicine, University of Ljubljana, Slovenia.
Nisteri Medicine and Research, Phoenix, AZ, USA.
Innovations (Phila). 2020 Sep/Oct;15(5):449-455. doi: 10.1177/1556984520938897. Epub 2020 Aug 6.
Cardiac conduction system disturbances potentially leading to permanent pacemaker implantation are significant postoperative complications after aortic valve replacement. The aim of this study was to assess the impact of sutureless prosthetic valve oversizing on permanent pacemaker implantation rate.
This multicenter retrospective study included 306 patients who underwent minimally invasive aortic valve replacement with the Perceval sutureless valve. Oversizing was determined by the implanted valve size indexed to body surface area. Data were analyzed with a multivariable logistic regression model.
This study confirmed excellent postoperative results for minimally invasive aortic valve replacement with right anterior minithoracotomy approach and rapid deployment sutureless valves. Mortality rate was 1%. Eighteen (5.9%) patients received a new permanent pacemaker. Multivariable logistic regression model ( = 0.05) found oversizing as significant risk factor ( = 0.017) for permanent postoperative pacemaker implantation independent of patient age. There was a significant negative correlation between the indexed implanted valve size and the mean and peak postoperative transvalvular gradients ( < 0.001).
Oversizing of sutureless prosthetic aortic valves is a risk factor for postoperative permanent pacemaker implantation. Proper sizing of Perceval is important to avoid complications and ensure optimal valve performance.
主动脉瓣置换术后,心脏传导系统紊乱可能导致永久性起搏器植入,这是一种严重的术后并发症。本研究旨在评估无缝线生物瓣瓣环过大对永久性起搏器植入率的影响。
本多中心回顾性研究纳入了 306 例行微创主动脉瓣置换术(使用 Perceval 无缝线生物瓣)的患者。瓣环过大是通过植入瓣膜的大小相对于体表面积来确定的。使用多变量逻辑回归模型进行数据分析。
本研究证实了经右前胸小切口和快速部署无缝线瓣膜行微创主动脉瓣置换术的良好术后效果。死亡率为 1%。18 例(5.9%)患者需要植入新的永久性起搏器。多变量逻辑回归模型( = 0.05)发现瓣环过大是永久性术后起搏器植入的显著危险因素( = 0.017),独立于患者年龄。植入瓣膜的指数大小与术后跨瓣压差的平均值和峰值呈显著负相关( < 0.001)。
无缝线生物瓣瓣环过大是术后永久性起搏器植入的危险因素。正确选择 Perceval 瓣环的大小对于避免并发症和确保最佳瓣膜性能非常重要。