Jaeger T M, Atkinson P P, Adams B A, Wright A J, Hurt R D
Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905.
Mayo Clin Proc. 1988 Jan;63(1):72-6. doi: 10.1016/s0025-6196(12)62667-6.
Legionella bozemanii, a rare cause of pneumonia, has a predilection for patients with impaired cellular immunity and underlying disease. We report the 12th culture-proven case of this infection, acquired in the community by a patient undergoing chemotherapy for chronic lymphocytic leukemia. The diagnosis was established when studies of bronchoalveolar lavage fluid produced a positive reaction with species-specific fluorescent antibody and growth on selective culture media. Although erythromycin was administered within 48 hours after the initial examination, the clinical condition did not improve substantially until rifampin was added to the antimicrobial regimen.
博兹曼军团菌是肺炎的罕见病因,易感染细胞免疫功能受损及患有基础疾病的患者。我们报告了第12例经培养证实的该感染病例,患者为一名正在接受慢性淋巴细胞白血病化疗的社区居民。当支气管肺泡灌洗液检测结果显示与种特异性荧光抗体呈阳性反应且在选择性培养基上生长时,确诊得以确立。尽管在初次检查后48小时内就使用了红霉素,但直到抗菌方案中加入利福平后,临床状况才得到显著改善。