Husmann Rachel, Lehman Alice, Nelson Ryan W, Pragman Alexa A
Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, 420 Delaware Street Southeast #D416, Minneapolis, MN 55455, USA.
Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, 420 Delaware Street Southeast #D416, Minneapolis, MN 55455, USA; Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Minnesota, 420 Delaware Street Southeast #850, Minneapolis, MN 55455, USA.
Clin Chest Med. 2025 Mar;46(1):61-75. doi: 10.1016/j.ccm.2024.10.005. Epub 2024 Nov 29.
This review of immunocompromised host pneumonia as the result of inborn errors of immunity (IEI) is organized by opportunistic pulmonary pathogen. The authors identify patients who warrant an evaluation for an IEI based on their clinical presentation. Their recommendations are guided by the immune defect(s) associated with each opportunistic pulmonary infection. Physicians without expertise in immunology may begin an evaluation for IEI using the guidance provided here. Comprehensive evaluation by an immunologist may also be warranted in many instances.
本综述将因先天性免疫缺陷（IEI）导致的免疫功能低下宿主肺炎按机会性肺部病原体进行组织编排。作者根据临床表现确定了需要对IEI进行评估的患者。他们的建议以与每种机会性肺部感染相关的免疫缺陷为指导。没有免疫学专业知识的医生可以利用本文提供的指导开始对IEI进行评估。在许多情况下，也可能需要免疫学家进行全面评估。
