Department of Neurosurgery, NYU Langone Health, New York, New York, USA.
Department of Neurology, NYU Langone Health, New York, New York, USA.
World Neurosurg. 2020 Dec;144:e80-e86. doi: 10.1016/j.wneu.2020.07.207. Epub 2020 Aug 3.
Venous thromboembolism (VTE) represents a significant source of morbidity and mortality in the inpatient population and is considered a leading preventable cause of death among inpatients. Neurosurgical inpatients are of particular interest because of the greater rates of immobility, steroid use, and potential consequences of postoperative hemorrhage. A consensus protocol for VTE screening in this population has not yet been developed, and institutional protocols vary widely.
We performed a retrospective review of lower extremity venous duplex ultrasonography (VDUS) usage at our institution and applied this information to the development of a neurosurgery department protocol, with consideration of high-risk patient risk factors and indications for VDUS ordering. We then implemented this protocol, which consisted of preoperative screening of patients at high risk of VTE and limited postoperative surveillance, for a 6-month period and compared VDUS usage and VTE occurrence.
Preoperative VDUS screening before nonemergent neurosurgical procedures in high-risk patients with active cancer, an inability to ambulate, or a history of deep vein thrombosis (DVT) identified proximal DVTs that were then treated. Postoperative routine surveillance VDUS scans only diagnosed incidental isolated calf DVT for which no clinically relevant sequelae occurred. Overall, postoperative surveillance VDUS usage decreased significantly (66.9% vs. 13.5%; P = 0.001).
Our findings lend support to preoperative screening of high-risk patients and suggest that routine postoperative VDUS surveillance of asymptomatic patients is unnecessary.
静脉血栓栓塞症(VTE)是住院患者发病率和死亡率的重要来源,被认为是住院患者死亡的主要可预防原因。神经外科住院患者特别值得关注,因为他们的活动受限率较高、使用类固醇药物的频率较高,且术后出血的潜在后果更为严重。目前尚未制定针对该人群的 VTE 筛查共识方案,各机构的方案差异很大。
我们对我院下肢静脉双功超声(VDUS)的使用情况进行了回顾性分析,并将这些信息应用于制定神经外科部门的方案,同时考虑了高危患者的风险因素和 VDUS 检查的适应证。然后,我们实施了该方案,即对有 VTE 高危风险的患者进行术前筛查,并对术后进行有限的监测,为期 6 个月,并比较了 VDUS 的使用情况和 VTE 的发生情况。
在有活动性癌症、无法行走或有深静脉血栓(DVT)病史的高危非紧急神经外科手术患者中,术前 VDUS 筛查可发现近端 DVT,随后进行治疗。术后常规监测 VDUS 扫描仅诊断出无症状孤立性小腿 DVT,未发生任何临床相关的后果。总体而言,术后监测 VDUS 的使用显著减少(66.9% vs. 13.5%;P=0.001)。
我们的研究结果支持对高危患者进行术前筛查,并表明对无症状患者进行常规术后 VDUS 监测是不必要的。