van Dam P A, Van Goethem M L, Kersschot E, Vervliet J, Van den Veyver I B, De Schepper A, Buytaert P
Department of Obstetrics and Gynecology, Antwerp University Hospital, Edegem, Belgium.
Radiology. 1988 Feb;166(2):435-9. doi: 10.1148/radiology.166.2.3275983.
The diagnostic virtues and limitations of single- and multimodality testing in the evaluation of solid palpable breast masses were studied. Two hundred one consecutive patients who had a solid palpable breast mass and who underwent biopsy between September 1982 and July 1986 were included for blinded retrospective analysis of their physical examination, mammographic, ultrasonographic (US), thermographic, and pathologic characteristics. Benign breast disease was diagnosed histologically in 106 women, while carcinoma was established in 95. The sensitivities of physical examination, mammography, US, and thermography were 0.88, 0.94, 0.78, and 0.49, respectively. US alone had the highest sensitivity in correct diagnosis of a benign solid breast mass and had the highest accuracy (0.84). Use of four modalities increased the preoperative diagnostic true-positive rate to 0.97, with some decline in specificity. Multimodality testing seems particularly beneficial in pre- and perimenopausal patients.
研究了单模态和多模态检测在可触及乳腺实性肿块评估中的诊断优势和局限性。纳入了1982年9月至1986年7月期间连续211例有可触及乳腺实性肿块且接受活检的患者，对其体格检查、乳腺X线摄影、超声（US）、热成像和病理特征进行盲法回顾性分析。106名女性经组织学诊断为良性乳腺疾病，95名确诊为癌。体格检查、乳腺X线摄影、超声和热成像的敏感性分别为0.88、0.94、0.78和0.49。单独使用超声在正确诊断良性乳腺实性肿块方面具有最高的敏感性，且准确性最高（0.84）。使用四种模态可将术前诊断真阳性率提高到0.97，但特异性有所下降。多模态检测在绝经前和围绝经期患者中似乎特别有益。
