Atkins P C, Martin G L, Yost R, Zweiman B
University of Pennsylvania School of Medicine, Department of Medicine, Philadelphia.
Ann Allergy. 1988 Jan;60(1):27-30.
We carried out sequential measurements of the intensity of simultaneously occurring late onset skin and bronchial reactivity in seven atopic subjects following skin and inhalation challenge with pollen antigen. All subjects demonstrated dual bronchial and cutaneous reactions. Although the intensity of the late onset bronchial responses correlated temporally and quantitatively with the degree of increase in serum neutrophil chemotactic activity, the intensity of the late onset skin responses correlated with the level of specific antigen-IgE in the serum. This suggests that even in the same subjects, different factors govern the intensity of late onset skin and bronchial responses.
我们对7名特应性受试者在接受花粉抗原皮肤和吸入激发后同时出现的迟发性皮肤和支气管反应强度进行了连续测量。所有受试者均表现出双相支气管和皮肤反应。虽然迟发性支气管反应的强度在时间和数量上与血清中性粒细胞趋化活性的增加程度相关，但迟发性皮肤反应的强度与血清中特异性抗原-IgE水平相关。这表明，即使在同一受试者中，不同因素也会影响迟发性皮肤和支气管反应的强度。
