Department of Biology, Johns Hopkins University, 3400 N. Charles St., 227 Mudd Hall, Baltimore, MD 21218, USA.
Department of Biology, Johns Hopkins University, 3400 N. Charles St., 227 Mudd Hall, Baltimore, MD 21218, USA.
Cell. 2020 Aug 6;182(3):539-541. doi: 10.1016/j.cell.2020.07.004.
In the skin, sympathetic nerves, arrector pili muscles, and hair follicles form a tri-lineage unit to cause piloerection or goosebumps. In this issue of Cell, Schwartz et al. report that, beyond goosebumps, muscle-anchored nerves form "synapse-like" connections with hair follicle stem cells to promote hair regeneration in response to cold.
在皮肤中,交感神经、立毛肌和毛囊形成一个三联体单元,引起毛发竖起或鸡皮疙瘩。在本期《细胞》杂志上,Schwartz 等人报道,除了鸡皮疙瘩之外,肌肉锚定神经还与毛囊干细胞形成“突触样”连接,以促进毛发在寒冷时的再生。