Departamento de Química Física, Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Zaragoza, Spain.
Departamento de Síntesis y Estructura de Biomoléculas, Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), Universidad de Zaragoza-CSIC, Spain.
Food Chem. 2021 Jan 30;336:127717. doi: 10.1016/j.foodchem.2020.127717. Epub 2020 Aug 1.
Continued industrialization and increasing environmental problems have highlighted the need to research new eco-friendly solvents, also known as deep eutectic solvents (DESs). To implement these solvents in industrial processes, the knowledge of their molecular organization and thermophysical properties must be enhanced. In this work, two DESs have been characterized: d-glucose:choline chloride:water (GCH) and d-glucose:citric acid:water (GCiH). NMR techniques were used to analyse both the supramolecular structure and the role of water and to calculate the diffusion coefficients. Moreover, seven thermophysical properties at several temperatures were evaluated. As a second aim, the solubility of quercetin was determined. NMR studies showed a stronger supramolecular structure of GCH and a high ratio of β-glucose in both DESs. Based on the thermophysical results, the solvent with choline chloride had the most compact fluid structure. Finally, the solubility of quercetin in the DESs was higher than in water, especially for GCH.
持续的工业化和日益严重的环境问题凸显了研究新型环保溶剂的必要性，这类溶剂也被称为深共晶溶剂（DESs）。为了在工业过程中应用这些溶剂，必须增强对其分子组织和热物理性质的了解。在这项工作中，我们对两种 DESs 进行了表征：葡萄糖：氯化胆碱：水（GCH）和葡萄糖：柠檬酸：水（GCiH）。我们使用 NMR 技术分析了超分子结构和水的作用，并计算了扩散系数。此外，我们还评估了在多个温度下的七种热物理性质。作为第二个目标，我们测定了槲皮素的溶解度。NMR 研究表明，GCH 的超分子结构更强，两种 DESs 中的β-葡萄糖比例也更高。基于热物理结果，含有氯化胆碱的溶剂具有最紧凑的流体结构。最后，与水相比，槲皮素在 DESs 中的溶解度更高，尤其是在 GCH 中。
