Department of Structural Mechanics, University of Granada, 18010 Granada, Spain.
Instituto de Investigación Biosanitaria, ibs.GRANADA, 18012 Granada, Spain.
Sensors (Basel). 2020 Aug 5;20(16):4362. doi: 10.3390/s20164362.
This paper presents the results of the comparison between a proposed Fourth Order Elastic Constants (FOECs) nonlinear model defined in the sense of Landau's theory, and the two most contrasted hyperelastic models in the literature, Mooney-Rivlin, and Ogden models. A mechanical testing protocol is developed to investigate the large-strain response of ex vivo cervical tissue samples in uniaxial tension in its two principal anatomical locations, the epithelial and connective layers. The final aim of this work is to compare the reconstructed shear modulus of the epithelial and connective layers of cervical tissue. According to the obtained results, the nonlinear parameter from the proposed FOEC model could be an important biomarker in cervical tissue diagnosis. In addition, the calculated shear modulus depended on the anatomical location of the cervical tissue (μepithelial = 1.29 ± 0.15 MPa, and μconnective = 3.60 ± 0.63 MPa).
本文呈现了一种基于朗道理论定义的四阶弹性常数（FOECs）非线性模型与文献中两种最具对比性的超弹性模型（Mooney-Rivlin 和 Ogden 模型）之间的比较结果。本文开发了一种力学测试方案，以研究离体颈椎组织样本在两个主要解剖位置（上皮层和结缔组织层）的单轴拉伸下的大应变响应。本工作的最终目的是比较颈椎组织上皮层和结缔组织层的重建剪切模量。根据所得结果，所提出的 FOEC 模型中的非线性参数β 可能是颈椎组织诊断的一个重要生物标志物。此外，计算出的剪切模量取决于颈椎组织的解剖位置（μepithelial = 1.29 ± 0.15 MPa，μconnective = 3.60 ± 0.63 MPa）。
