Jin Jing-Jing, Xu Tian-Tian, Li Yan-Fang, Wang Hong-Yang, Zhang Dan, Zhang Pan-Pan, Xu Li-Xin, Wang Chun-Xiu, Fan Zhu, Wang Ling, Liu Chen, Wang Shuang, Shi Hao-Tian, Li Cai-Hong, Zhang Hai-Fang, Huang Yan
Department of Respiratory Medicine, North China University of Science and Technology Affiliated Hospital, Tangshan, Hebei 063000, People's Republic of China.
Department of Pediatric Medicine, Hebei People's Hospital Affiliated to North China University of Science and Technology, Shijiazhuang, Hebei 050000, People's Republic of China.
Cancer Manag Res. 2020 Jul 17;12:5903-5907. doi: 10.2147/CMAR.S241618. eCollection 2020.
This study investigates the effect of the standardized management of cancer pain on patients with bone metastasis of lung cancer in China.
A total of 123 patients with bone metastasis of lung cancer were selected from the Respiratory Department of the Affiliated Hospital of North China University of Science and Technology. Among these patients, 62 patients who had not received standardized management of cancer pain from March 12, 2018, to September 11, 2018, were selected as the control group. In contrast, 61 patients who had received the standardized management of cancer pain from September 12, 2018, to March 11, 2019, were selected as the observation group. The former cohort accepted the conventional management of cancer pain, while the latter accepted the strict, standardized management of cancer pain. The demographic statistics, disease characteristics, and painkiller application of patients in these two groups were analyzed. Then, the analgesic effect and level of satisfaction were compared between these two groups.
No significant differences were noticed between these two groups in terms of age, gender, smoking status, type of pathology, education level, previous treatment, and the Eastern Cooperative Oncology Group score, as well as other demographic and disease characteristics. As for the use of painkillers, opioid analgesics accounted for a higher proportion in the observation group than in the control group. Compared with the control group, pain improvement and patient satisfaction after analgesic treatment were significantly higher in the observation group ( < 0.05).
The standardized management of cancer pain can considerably alleviate the pain of patients with bone metastasis of lung cancer and improve their quality of life. Furthermore, this type of management can increase satisfaction.
本研究旨在调查癌症疼痛标准化管理对中国肺癌骨转移患者的影响。
从华北理工大学附属医院呼吸科选取123例肺癌骨转移患者。其中，将2018年3月12日至2018年9月11日未接受癌症疼痛标准化管理的62例患者作为对照组。相比之下，将2018年9月12日至2019年3月11日接受癌症疼痛标准化管理的61例患者作为观察组。前一组接受癌症疼痛的常规管理，而后一组接受严格的癌症疼痛标准化管理。分析两组患者的人口统计学统计数据、疾病特征和止痛药应用情况。然后，比较两组之间的镇痛效果和满意度水平。
两组在年龄、性别、吸烟状况、病理类型、教育程度、既往治疗情况、东部肿瘤协作组评分以及其他人口统计学和疾病特征方面均未发现显著差异。在止痛药使用方面，观察组阿片类镇痛药的使用比例高于对照组。与对照组相比，观察组镇痛治疗后的疼痛改善情况和患者满意度显著更高（<0.05）。
癌症疼痛标准化管理可显著减轻肺癌骨转移患者的疼痛并提高其生活质量。此外，这种管理方式可提高满意度。
