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Legal medicine implications in fibrinolytic therapy of acute ischemic stroke.法医学在急性缺血性脑卒中溶栓治疗中的应用。
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Applications of Antioxidants in Metabolic Disorders and Degenerative Diseases: Mechanistic Approach.抗氧化剂在代谢紊乱和退行性疾病中的应用:机制探讨
Oxid Med Cell Longev. 2019 Jul 29;2019:4179676. doi: 10.1155/2019/4179676. eCollection 2019.
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Effects of combining modern recovery techniques with neurotrophic medication and standard treatment in stroke patients.联合现代康复技术与神经营养药物和标准治疗对脑卒中患者的影响。
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Long-Term Resveratrol Supplementation as a Secondary Prophylaxis for Stroke.长期白藜芦醇补充作为中风的二级预防。
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Painful tonic spasms and brainstem involvement in a patient with neuromyelitis optica spectrum disorder.视神经脊髓炎谱系障碍患者的疼痛性强直性痉挛与脑干受累
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Psychological treatments for depression and anxiety in dementia and mild cognitive impairment: systematic review and meta-analysis.痴呆症和轻度认知障碍中抑郁症和焦虑症的心理治疗:系统评价与荟萃分析
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Cerebrospinal fluid biomarkers in Alzheimer's disease, vascular dementia and ischemic stroke patients: a critical analysis.阿尔茨海默病、血管性痴呆和缺血性脑卒中患者的脑脊液生物标志物:批判性分析。
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阿尔茨海默病和中风所致神经认知障碍中的精神痛苦。

Distress in neurocognitive disorders due to Alzheimer's disease and stroke.

作者信息

Dindelegan Camelia Maria, Faur Darian, Purza Lavinia, Bumbu Adrian, Sabau Monica

机构信息

Psychology Department, Faculty of Social Humanistic Science, University of Oradea, 410087 Oradea, Romania.

Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania.

出版信息

Exp Ther Med. 2020 Sep;20(3):2501-2509. doi: 10.3892/etm.2020.8806. Epub 2020 May 28.

DOI:10.3892/etm.2020.8806
PMID:32765742
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7401825/
Abstract

Patients with neurocognitive disorders experience subjectively the concept of quality of life; this is the reason why researchers avoid approaching this concept and prefer to focus attention on the emotional profile of the caregivers. Many studies highlight the efforts both emotional and financial made by caregivers in case of patients diagnosed with neurocognitive disorders. The present study shows the differences between the patients diagnosed with neurocognitive disorder due to Alzheimer's disease and patients diagnosed with stroke, as well as the Romanian norms for the short form of Geriatric Depression Scale. The study group consisted of the clinical population (N=45), selected according to the inclusion/exclusion criteria, following the principles of Helsinki Declaration for Ethical Medical Research. The study was conducted at the Neuropsychiatry section of the Municipal Clinical Hospital, Dr Gavril Curteanu, Oradea, Romania. The results showed significant differences between the two types of patients in terms of quality of life, t(43)=-7.99, P=0.001, affective distress, t(43)=5.10, P=0.001 and perceived stress, t(43)=3.81, P=0.001. The internal consistency of the scale is high, the coefficient KR-20 being 0.86.

摘要

患有神经认知障碍的患者主观上体验着生活质量的概念;这就是研究人员避免探讨这一概念而更倾向于关注照料者情感状况的原因。许多研究强调了在诊断为神经认知障碍的患者情况下,照料者在情感和经济方面付出的努力。本研究展示了诊断为阿尔茨海默病所致神经认知障碍的患者与诊断为中风的患者之间的差异,以及老年抑郁量表简表的罗马尼亚常模。研究组由根据纳入/排除标准选取的临床人群(N = 45)组成,遵循赫尔辛基宣言关于医学伦理研究的原则。该研究在罗马尼亚奥拉迪亚市加夫里尔·库尔泰亚努博士市立临床医院的神经精神科进行。结果显示,在生活质量方面,两种类型的患者存在显著差异,t(43)= -7.99,P = 0.001;情感困扰方面,t(43)= 5.10,P = 0.001;感知压力方面,t(43)= 3.81,P = 0.001。该量表的内部一致性较高,KR - 20系数为0.86。