Department of Bioinformatics and Biochemistry, Technische Universität Braunschweig, Braunschweig, 38106, Germany.
Braunschweig Integrated Centre of Systems Biology, Technische Universität Braunschweig, Braunschweig, 38106, Germany.
F1000Res. 2020 Apr 24;9:288. doi: 10.12688/f1000research.23427.2. eCollection 2020.
Metabolic pathways are an important part of systems biology research since they illustrate complex interactions between metabolites, enzymes, and regulators. Pathway maps are drawn to elucidate metabolism or to set data in a metabolic context. We present MetaboMAPS, a web-based platform to visualize numerical data on individual metabolic pathway maps. Metabolic maps can be stored, distributed and downloaded in SVG-format. MetaboMAPS was designed for users without computational background and supports pathway sharing without strict conventions. In addition to existing applications that established standards for well-studied pathways, MetaboMAPS offers a niche for individual, customized pathways beyond common knowledge, supporting ongoing research by creating publication-ready visualizations of experimental data.
代谢途径是系统生物学研究的一个重要部分，因为它们说明了代谢物、酶和调节剂之间的复杂相互作用。途径图用于阐明代谢或在代谢背景下设置数据。我们提出了 MetaboMAPS，这是一个基于网络的平台，用于可视化单个代谢途径图上的数值数据。代谢图可以以 SVG 格式存储、分发和下载。MetaboMAPS 专为没有计算背景的用户设计，支持无需严格约定的途径共享。除了为研究充分的途径建立标准的现有应用程序外，MetaboMAPS 还为超越常识的个性化、定制途径提供了一个利基市场，通过为实验数据创建可发布的可视化效果，支持正在进行的研究。
