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机器人技术在非小细胞肺癌外科治疗中的应用

Use of Robotics in Surgical Treatment of Non-small Cell Lung Cancer.

作者信息

Berzenji Lawek, Yogeswaran Krishan, Van Schil Paul, Lauwers Patrick, Hendriks Jeroen M H

机构信息

Department of Thoracic and Vascular Surgery, University Hospital of Antwerp, Antwerp University, Level 2, Route 146, Wilrijkstraat 10, B-2650, Edegem (Antwerp), Belgium.

出版信息

Curr Treat Options Oncol. 2020 Aug 7;21(10):80. doi: 10.1007/s11864-020-00778-0.

Abstract

Robotic-assisted videothoracoscopic surgery (R-VATS) has become increasingly popular and widely used since its introduction and is nowadays considered a standard treatment approach in many centres for the treatment of non-small cell lung cancer. R-VATS was initially developed to overcome the drawbacks of VATS by offering surgeons more flexibility and three-dimensional optics during thoracoscopic surgery. The effectiveness of R-VATS lobectomy regarding oncological outcomes, morbidity, mortality, and postoperative quality of life (QoL) has been shown in an increasing number of studies. More recently, these results have also been corroborated for sublobar resections, more specifically for segmentectomy. However, no well-powered, multicentre randomized trials have been performed to demonstrate the superiority of R-VATS compared with open surgery or conventional types of VATS (total VATS, uniportal VATS, etc.). The majority of the evidence currently available is based on non-randomized studies, and many studies report conflicting results when comparing R-VATS and conventional VATS. Moreover, there is a lack of data regarding the cost and the cost-efficiency of robotic surgery compared with VATS and open surgery. Current evidence suggests that R-VATS costs are higher than VATS and that a deficit can only be prevented when up to 150-300 thoracic surgery procedures are performed annually. Finally, robotic-assisted laparoscopic surgery showed better ergonomics and reduced musculoskeletal disorders compared with non-robotic laparoscopic surgery.

摘要

自引入以来,机器人辅助电视胸腔镜手术(R-VATS)越来越受欢迎且应用广泛,如今在许多中心已被视为治疗非小细胞肺癌的标准治疗方法。R-VATS最初是为克服电视胸腔镜手术(VATS)的缺点而开发的,它能在胸腔镜手术中为外科医生提供更大的灵活性和三维视野。越来越多的研究表明了R-VATS肺叶切除术在肿瘤学疗效、发病率、死亡率和术后生活质量(QoL)方面的有效性。最近,这些结果在亚肺叶切除术中也得到了证实,更具体地说是在肺段切除术中。然而,尚未进行有力的多中心随机试验来证明R-VATS相对于开放手术或传统类型的VATS(全胸腔镜手术、单孔胸腔镜手术等)的优越性。目前可得的大多数证据基于非随机研究,并且许多研究在比较R-VATS和传统VATS时报告了相互矛盾的结果。此外,与VATS和开放手术相比,缺乏关于机器人手术成本和成本效益的数据。目前的证据表明,R-VATS的成本高于VATS,只有每年进行多达150 - 300例胸外科手术才能防止出现亏损。最后,与非机器人腹腔镜手术相比,机器人辅助腹腔镜手术显示出更好的人体工程学效果并减少了肌肉骨骼疾病。

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