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妊娠糖尿病患者餐后90分钟血糖水平与60分钟和120分钟血糖水平的比较:一项前瞻性队列研究。

Comparison of postprandial 90th-minute plasma glucose level with 60th- and 120th-minute levels in patients with gestational diabetes: a prospective cohort study.

作者信息

Sever Ozge, Sarsmaz Kemal, Ozgu-Erdinc A S, Yucel Aykan

机构信息

University of Health Sciences, Etlik Zubeyde Hanim Woman's Health Care, Training and Research Hospital, Perinatology Department, Ankara, Turkey.

Ministry of Health, Ankara City Hospital, Ankara, Turkey.

出版信息

Endocrine. 2021 Jan;71(1):69-75. doi: 10.1007/s12020-020-02447-6. Epub 2020 Aug 7.

DOI:10.1007/s12020-020-02447-6
PMID:32767192
Abstract

PURPOSE

The objective of the present study is to compare postprandial 90th-minute plasma glucose measurement with fasting, postprandial 60 and 120 min in gestational diabetes mellitus (GDM).

METHODS

One hundred and thirty-one pregnant women with GDM were hospitalized for regulation of maternal plasma glucose levels. Plasma glucose levels were daily recorded for every patient and treatment option arranged without considering the 90th-minute plasma glucose level. All patients were followed up until birth and pregnancy results were compared.

RESULT

At the admission, 69% of our patients were on diet and 31% were on insulin with diet therapy. The highest postprandial mean plasma glucose was seen at 90 min after breakfast (137.50 mg/dl), at 60 min after lunch (137.80 mg/dl), and 60 min after dinner (134.50 mg/dl). The cut-off level for postprandial glucose at 90th minute was determined as 130 mg/dl. The upper limit plasma glucose levels were most frequently exceeded at 90th minute for each meal. High plasma glucose levels and the need for neonatal intensive care unit were correlated (p < 0.05).

CONCLUSIONS

The highest plasma glucose level was seen at 90 min after breakfast, 60 min after lunch, and 60 min after dinner. The upper limit plasma glucose levels were most frequently exceeded at the 90 min.

摘要

目的

本研究的目的是比较妊娠期糖尿病(GDM)患者餐后90分钟血糖测量值与空腹血糖、餐后60分钟及120分钟血糖值。

方法

131例GDM孕妇住院以调节母体血糖水平。每天记录每位患者的血糖水平,并在不考虑餐后90分钟血糖水平的情况下安排治疗方案。所有患者随访至分娩,并比较妊娠结果。

结果

入院时,69%的患者接受饮食治疗,31%的患者接受胰岛素联合饮食治疗。早餐后90分钟(137.50mg/dl)、午餐后60分钟(137.80mg/dl)和晚餐后60分钟(134.50mg/dl)的餐后平均血糖最高。餐后90分钟血糖的临界值确定为130mg/dl。每餐在90分钟时血浆葡萄糖水平上限最常被超过。高血糖水平与新生儿重症监护病房需求相关(p<0.05)。

结论

早餐后90分钟、午餐后60分钟和晚餐后60分钟血糖水平最高。血浆葡萄糖水平上限在90分钟时最常被超过。

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