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引入新的治疗方案可减少老年女性初次全髋关节置换术后股骨假体周围骨折的发生。

Introduction of a New Treatment Algorithm Reduces the Number of Periprosthetic Femoral Fractures After Primary Total Hip Arthroplasty in Elderly Females.

机构信息

Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Orthopedic Surgery, Copenhagen University Hvidovre Hospital, Copenhagen, Denmark.

Department of Orthopedic Surgery, Copenhagen University Hvidovre Hospital, Copenhagen, Denmark.

出版信息

J Arthroplasty. 2020 Dec;35(12):3613-3620. doi: 10.1016/j.arth.2020.06.077. Epub 2020 Jul 14.

Abstract

BACKGROUND

Increasing global usage of cementless prostheses in total hip arthroplasty (THA) presents a challenge, especially for elderly patients. To reduce the risk of early periprosthetic femoral fractures (PFFs), a new treatment algorithm for females older than 60 years undergoing primary THA was introduced. The aim of this study was to determine the impact of the new treatment algorithm on the early risk of perioperative and postoperative PFFs and guideline compliance.

METHODS

A total of 2405 consecutive THAs that underwent primary unilateral THA at our institution were retrospectively identified in the period January 1, 2013-December 31, 2018. A new treatment algorithm was introduced on April 1, 2017 with female patients aged older than 60 years intended to receive cemented femoral components. Before this, all patients were scheduled to receive cementless femoral components. Demographic data, number of perioperative and postoperative PFFs, and surgical compliance were recorded, analyzed, and intergroup differences compared.

RESULTS

The utilization of cemented components in female patients older than 60 years increased from 12.3% (n = 102) to 82.5% (n = 264). In females older than 60 years, a significant reduction in the risk in early postoperative and intraoperative PFF after introduction of the new treatment algorithm was seen (4.57% vs 1.25%; P = .007 and 2.29% vs 0.31%; P = .02, respectively). Overall risk for postoperative and intraoperative fractures combined was also reduced in the entire cohort (4.1% vs 2.0%; P = .01).

CONCLUSION

Use of cemented fixation of the femoral component in female patients older than 60 years significantly reduces the number of PFFs. Our findings support use of cemented femoral fixation in elderly female patients.

摘要

背景

在全髋关节置换术(THA)中,越来越多的人使用非骨水泥假体,这对老年患者来说是一个挑战。为了降低早期人工假体周围股骨骨折(PFF)的风险,为 60 岁以上女性接受初次 THA 引入了一种新的治疗方案。本研究旨在确定新治疗方案对围手术期和术后 PFF 的早期风险以及指南遵循情况的影响。

方法

回顾性分析 2013 年 1 月 1 日至 2018 年 12 月 31 日在我院行初次单侧 THA 的 2405 例连续病例。2017 年 4 月 1 日引入了一种新的治疗方案,建议 60 岁以上女性患者使用骨水泥股骨假体。在此之前,所有患者均计划使用非骨水泥股骨假体。记录并分析人口统计学数据、围手术期和术后 PFF 的数量以及手术依从性,并进行组间比较。

结果

60 岁以上女性患者使用骨水泥假体的比例从 12.3%(n=102)增加到 82.5%(n=264)。引入新治疗方案后,60 岁以上女性患者的早期术后和术中 PFF 风险显著降低(4.57%比 1.25%;P=0.007 和 2.29%比 0.31%;P=0.02)。整个队列的术后和术中骨折综合风险也降低(4.1%比 2.0%;P=0.01)。

结论

在 60 岁以上女性患者中使用骨水泥固定股骨假体可显著降低 PFF 的数量。我们的发现支持在老年女性患者中使用骨水泥股骨固定。

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