Department of Pathology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Department of Radiodiagnosis, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Indian J Pathol Microbiol. 2020 Jul-Sep;63(3):456-459. doi: 10.4103/IJPM.IJPM_267_19.
An elderly adult woman presented with upper abdominal pain to the urology department. Imaging studies revealed a right adrenal lesion with central necrosis, abutting the large vessels and suggestive of malignancy. Histopathology showed an encapsulated spindle cell tumor with marked nuclear atypia, cystic change, and hemorrhage. S100 immunomarker was strongly and diffusely positive. Final diagnosis was ancient schwannoma with secondary change. Schwannomas are rare in the adrenal gland, with <50 cases reported in the literature. These incidentally detected nonfunctional adrenal tumors need confirmation with histopathology and ancillary studies.
一位老年女性因上腹痛到泌尿科就诊。影像学检查显示右侧肾上腺有一处病灶，伴中央坏死，与大血管相邻，提示恶性肿瘤。组织病理学显示为包膜梭形细胞肿瘤，细胞核异型性明显，囊性变和出血。S100 免疫标志物呈强弥漫阳性。最终诊断为伴有继发性改变的古老神经鞘瘤。神经鞘瘤在肾上腺中罕见，文献中报道的病例不足 50 例。这些偶然发现的无功能性肾上腺肿瘤需要通过组织病理学和辅助研究来证实。
