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原发性肾病综合征患儿合理用药指标体系的实证研究:一项横断面研究。

An empirical study on the index system of rational drug use in children with primary nephrotic syndrome: A cross-sectional study.

作者信息

Lin Mao, Huang Liang, Zeng Linan, Zhang Lingli

机构信息

Department of Pharmacy.

Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University.

出版信息

Medicine (Baltimore). 2020 Aug 7;99(32):e21564. doi: 10.1097/MD.0000000000021564.

Abstract

In the study's early stage, the research group had established an evaluation index system for the rational drug use of primary nephrotic syndrome in children. To assess the feasibility of the established index system, we conducted this empirical study.The cross-sectional study was conducted by using the Hospital Information System to extract some general clinical data of hospitalized children with primary nephrotic syndrome, which included registration number, age, sex, diagnosis and medication, etc. Utilize the SPSS23.0 software and Excel 2016 to descriptively analyze information.224 hospitalized children with primary nephrotic syndrome who met the inclusion criteria were included, ranging from 18 years old and 10 months to 11 months and 23 days, with an average age of 8.40, plus or minus 4.30 years. 148 males (66.07%) and 76 females (33.93%). The duration of hospitalization was 1-57 days, with an average hospitalization time of 10.59 days. The most common is respiratory infections, such as the bronchopneumonia, the mycoplasma pneumonia, etc. This study had successfully completed the measurement of the evaluation index system for the rational drug use of primary nephrotic syndrome in children.All indicators are feasible, but the operability and applicability need further research and improvement.

摘要

在该研究的早期阶段,研究小组建立了儿童原发性肾病综合征合理用药的评价指标体系。为评估所建立指标体系的可行性,我们开展了这项实证研究。通过医院信息系统进行横断面研究,提取住院的儿童原发性肾病综合征患者的一些一般临床资料,包括住院号、年龄、性别、诊断及用药等情况。利用SPSS23.0软件和Excel 2016对信息进行描述性分析。纳入符合纳入标准的224例住院儿童原发性肾病综合征患者,年龄范围为18岁10个月至11个月23天,平均年龄8.40岁,±4.30岁。男性148例(66.07%),女性76例(33.93%)。住院时间为1 - 57天,平均住院时间为10.59天。最常见的是呼吸道感染,如支气管肺炎、支原体肺炎等。本研究成功完成了儿童原发性肾病综合征合理用药评价指标体系的测评。所有指标均可行,但可操作性和适用性有待进一步研究和改进。

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