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本文引用的文献

1
Indicators for assessing quality of drug use: A systematic literature review.评估药物使用质量的指标:一项系统的文献综述。
J Evid Based Med. 2017 Aug;10(3):222-232. doi: 10.1111/jebm.12244. Epub 2017 May 24.
2
Bioavailable vitamin D levels are reduced and correlate with bone mineral density and markers of mineral metabolism in adults with nephrotic syndrome.肾病综合征成人患者的生物可利用维生素D水平降低,且与骨矿物质密度及矿物质代谢标志物相关。
Nephrology (Carlton). 2016 Jun;21(6):483-9. doi: 10.1111/nep.12638.
3
Clinical practice guideline for pediatric idiopathic nephrotic syndrome 2013: general therapy.《2013年儿童特发性肾病综合征临床实践指南:一般治疗》
Clin Exp Nephrol. 2015 Feb;19(1):34-53. doi: 10.1007/s10157-014-1031-9.
4
Canadian Society of Nephrology commentary on the 2012 KDIGO clinical practice guideline for the management of blood pressure in CKD.加拿大肾脏病学会关于 2012 年 KDIGO 慢性肾脏病血压管理临床实践指南的评论。
Am J Kidney Dis. 2014 Jun;63(6):869-87. doi: 10.1053/j.ajkd.2014.03.003. Epub 2014 Apr 12.
5
Effects of cyclosporine on bone mineral density in patients with glucocorticoid-dependent nephrotic syndrome in remission.环孢素对缓解期糖皮质激素依赖型肾病综合征患者骨密度的影响。
Int Urol Nephrol. 2013 Jun;45(3):803-8. doi: 10.1007/s11255-012-0264-3. Epub 2012 Sep 7.
6
Nephrotic syndrome after oral bisphosphonate (alendronate) administration in a patient with osteoporosis.骨质疏松症患者口服双膦酸盐(阿仑膦酸钠)后出现肾病综合征。
Osteoporos Int. 2012 Jul;23(7):2059-62. doi: 10.1007/s00198-011-1836-2. Epub 2012 Jan 26.
7
Randomized cross-over trial comparing albumin and frusemide infusions in nephrotic syndrome.比较白蛋白和速尿输注治疗肾病综合征的随机交叉试验。
Pediatr Nephrol. 2009 Apr;24(4):775-82. doi: 10.1007/s00467-008-1062-0. Epub 2009 Jan 14.
8
[Commentary to the article: ONTARGET Investigators, Yusuf S, Teo KK, Pogue J et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med 2008; 358: 1547-59].[对文章的评论:ONTARGET研究组,尤素福·S、郑克勤、波格·J等。替米沙坦、雷米普利或两者联合用于血管事件高危患者。《新英格兰医学杂志》2008年;358: 1547 - 59]
Kardiol Pol. 2008 Jun;66(6):705-6; discussion 707.
9
Nephrotic syndrome associated with human parvovirus B19 infection.与人类细小病毒B19感染相关的肾病综合征
Pediatr Nephrol. 2003 Mar;18(3):280-2. doi: 10.1007/s00467-002-1056-2. Epub 2003 Feb 12.
10
High dose methylprednisolone therapy in nephrotic syndrome.大剂量甲基强的松龙治疗肾病综合征。
Indian J Pediatr. 1999 Mar-Apr;66(2):171-4. doi: 10.1007/BF02761198.

原发性肾病综合征患儿合理用药指标体系的实证研究:一项横断面研究。

An empirical study on the index system of rational drug use in children with primary nephrotic syndrome: A cross-sectional study.

作者信息

Lin Mao, Huang Liang, Zeng Linan, Zhang Lingli

机构信息

Department of Pharmacy.

Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University.

出版信息

Medicine (Baltimore). 2020 Aug 7;99(32):e21564. doi: 10.1097/MD.0000000000021564.

DOI:10.1097/MD.0000000000021564
PMID:32769899
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7593002/
Abstract

In the study's early stage, the research group had established an evaluation index system for the rational drug use of primary nephrotic syndrome in children. To assess the feasibility of the established index system, we conducted this empirical study.The cross-sectional study was conducted by using the Hospital Information System to extract some general clinical data of hospitalized children with primary nephrotic syndrome, which included registration number, age, sex, diagnosis and medication, etc. Utilize the SPSS23.0 software and Excel 2016 to descriptively analyze information.224 hospitalized children with primary nephrotic syndrome who met the inclusion criteria were included, ranging from 18 years old and 10 months to 11 months and 23 days, with an average age of 8.40, plus or minus 4.30 years. 148 males (66.07%) and 76 females (33.93%). The duration of hospitalization was 1-57 days, with an average hospitalization time of 10.59 days. The most common is respiratory infections, such as the bronchopneumonia, the mycoplasma pneumonia, etc. This study had successfully completed the measurement of the evaluation index system for the rational drug use of primary nephrotic syndrome in children.All indicators are feasible, but the operability and applicability need further research and improvement.

摘要

在该研究的早期阶段,研究小组建立了儿童原发性肾病综合征合理用药的评价指标体系。为评估所建立指标体系的可行性,我们开展了这项实证研究。通过医院信息系统进行横断面研究,提取住院的儿童原发性肾病综合征患者的一些一般临床资料,包括住院号、年龄、性别、诊断及用药等情况。利用SPSS23.0软件和Excel 2016对信息进行描述性分析。纳入符合纳入标准的224例住院儿童原发性肾病综合征患者,年龄范围为18岁10个月至11个月23天,平均年龄8.40岁,±4.30岁。男性148例(66.07%),女性76例(33.93%)。住院时间为1 - 57天,平均住院时间为10.59天。最常见的是呼吸道感染,如支气管肺炎、支原体肺炎等。本研究成功完成了儿童原发性肾病综合征合理用药评价指标体系的测评。所有指标均可行,但可操作性和适用性有待进一步研究和改进。