早期肠内营养支持对急性重症胰腺炎治疗的效果：一项系统评价方案
Effect of early enteral nutrition support for the management of acute severe pancreatitis: A protocol of systematic review.
作者信息
Guo Yong-Bo, Liu Yan, Ma Jing, Cai Ying, Jiang Xiao-Ming, Zhang Hong
机构信息
Department of Critical Care Medicine, The Affiliated Hongqi Hospital of Mudanjiang Medical University.
Department of Critical Care Medicine, First Affiliated Hospital of Mudanjiang Medical University, Mudanjiang.
出版信息
Medicine (Baltimore). 2020 Aug 7;99(32):e21569. doi: 10.1097/MD.0000000000021569.
BACKGROUND
This study aims to assess the effect of early enteral nutrition support (EENS) for the management of acute severe pancreatitis (ASP).
METHODS
This study will search Cochrane Library, PUBMED, EMBASE, Cumulative Index to Nursing and Allied Health Literature, Allied and Complementary Medicine Database, CNKI, and WANGFANG from their inception to the present without language limitations. In addition, this study will also search clinical trial registry and reference lists of included trials. Eligible comparators will be standard care, medications, and any other interventions. Two authors will independently scan all citations, titles/abstracts, and full-text studies. The study methodological quality will be appraised using Cochrane risk of bias tool. If it is possible, we will pool out data and perform meta-analysis. Strength of evidence for each main outcome will be evaluated using the Grading of Recommendations Assessment, Development, and Evaluation.
RESULTS
This study will summarize the most recent evidence to assess the effect of EENS for the management of ASP.
CONCLUSION
The findings of this study will help to determine whether EENS is effective for patients with ASP.
STUDY REGISTRATION
INPLASY202070009.
背景
本研究旨在评估早期肠内营养支持（EENS）对急性重症胰腺炎（ASP）治疗的效果。
方法
本研究将检索Cochrane图书馆、PUBMED、EMBASE、护理学与健康相关文献累积索引、补充与替代医学数据库、中国知网和万方数据库，检索时间从建库至目前，无语言限制。此外，本研究还将检索临床试验注册库及纳入试验的参考文献列表。符合条件的对照将为标准治疗、药物及任何其他干预措施。两名作者将独立筛选所有文献、标题/摘要及全文研究。研究方法学质量将使用Cochrane偏倚风险工具进行评估。若可行，我们将汇总数据并进行荟萃分析。每个主要结局的证据强度将使用推荐分级评估、制定与评价系统进行评估。
结果
本研究将总结最新证据，以评估EENS对ASP治疗的效果。
结论
本研究结果将有助于确定EENS对ASP患者是否有效。
研究注册
INPLASY202070009。
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