Zhao Wei, Li Jun, Chen Hengwen, Wu Qingjuan, Deng Yawen, Tan Yuqing
Guang 'anmen Hospital, China Academy of Traditional Chinese Medicine.
Beijing University of Chinese Medicine, Beijing, China.
Medicine (Baltimore). 2020 Aug 7;99(32):e21590. doi: 10.1097/MD.0000000000021590.
As one of the common cardiovascular diseases, acute myocardial infarction (AMI) is characterized by a high mortality rate, frequent complications, and a serious threat to human health and quality of life. Traditional Chinese medicine injection (TCMI) has been used clinically to treat AMI; however, there is no uniform standard for clinical treatment of AMI. The purpose of this study is to evaluate the efficacy and safety of different TCMI by using systematic review and network meta-analysis.
According to the strategy, the authors will retrieve both 4 Chinese databases and 3 English databases by June 30, 2020. After a series of screening, randomized controlled trials will be included related to TCMI for AMI. Two researchers will use Aggregate Data Drug Information System and STATA 15.0 to analyze the data. Finally, the evidence grade of the results will be evaluated.
This study will provide a reliable evidence for the selection of TCMI therapies for AMI.
The results of this study will provide references for evaluating the influence of different TCMI therapies for AMI, and provide decision-making references for clinical research.
DOI 10.17605/OSF.IO/FYGBT.
急性心肌梗死（AMI）作为常见的心血管疾病之一，具有死亡率高、并发症频发的特点，严重威胁人类健康和生活质量。中药注射剂（TCMI）已被临床用于治疗AMI；然而，AMI的临床治疗尚无统一标准。本研究的目的是通过系统评价和网络荟萃分析评估不同中药注射剂的疗效和安全性。
根据研究策略，作者将于2020年6月30日前检索4个中文数据库和3个英文数据库。经过一系列筛选，将纳入与治疗AMI的中药注射剂相关的随机对照试验。两名研究人员将使用综合数据药物信息系统和STATA 15.0进行数据分析。最后，将对结果的证据等级进行评估。
本研究将为AMI的中药注射剂治疗选择提供可靠证据。
本研究结果将为评估不同中药注射剂治疗AMI的影响提供参考，并为临床研究提供决策参考。
DOI 10.17605/OSF.IO/FYGBT。
