Pestrea Catalin, Gherghina Alexandra, Ortan Florin, Cismaru Gabriel, Radu Rosu
Department of Interventional Cardiology, Brasov County Emergency Clinical Hospital.
5th Department of Internal Medicine, Cardiology-Rehabilitation, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania.
Medicine (Baltimore). 2020 Aug 7;99(32):e21602. doi: 10.1097/MD.0000000000021602.
Recent studies have shown that His-bundle pacing could be an alternative in patients requiring cardiac resynchronization therapy as it is comparable or better in terms of amelioration of ventricular activation, narrowing of the QRS complex, or clinical outcomes. However, in case of high threshold at the level of His-bundle or inability to correct conduction through a diseased His-Purkinje system other option should be searched like left bundle pacing.
A 77-year-old man presented to the Emergency Department for dizziness and dizziness and lightheadedness due to an intermittent 2:1 atrioventricular block with a QRS complex morphology of a major left branch block.
Given the documented symptomatic 2:1 AV block, according to the European Guideliness the patient was considered to have a class 1 indication of permanent double chamber cardiostimulation.
A lead delivery system with a C315 His catheter and a Select Secure 3830 69 cm pacing lead were placed at the His bundle area with important narrowing of the QRS complex but with an unacceptable high threshold. The delivery system was moved towards the apex 1,5 cm and the lead screwed deep into the septum until capture of the left bundle branch was achieved with complete normalization of the conduction troubles.
At 3 month follow-up the patient was asymptomatic and the pacing and sensing thresholds remained at same values as during implantation: 0.75/0.4 ms and 14 mV respectively.
Left bundle-pacing represents the next step of His-Purkinje system pacing to overcome all difficulties related to His-bundle pacing.
近期研究表明,希氏束起搏对于需要心脏再同步治疗的患者可能是一种替代方法,因为在改善心室激动、缩窄QRS波群或临床结局方面,它具有可比性或更好的效果。然而,如果希氏束水平阈值较高或无法通过病变的希氏-浦肯野系统纠正传导,则应寻找其他选择,如左束支起搏。
一名77岁男性因间歇性2:1房室传导阻滞伴主要左束支阻滞的QRS波群形态,出现头晕、眩晕和头晕目眩症状,前往急诊科就诊。
鉴于记录的有症状的2:1房室传导阻滞,根据欧洲指南,该患者被认为有永久性双腔心脏起搏的I类适应证。
使用带有C315希氏导管和Select Secure 3830 69厘米起搏导线的导线输送系统,放置在希氏束区域,QRS波群明显缩窄,但阈值高得无法接受。将输送系统向心尖移动1.5厘米,导线深深拧入间隔,直至实现左束支捕获,传导障碍完全恢复正常。
在3个月的随访中,患者无症状,起搏和感知阈值保持在植入时的相同水平:分别为0.75/0.4毫秒和14毫伏。
左束支起搏是希氏-浦肯野系统起搏的下一步,以克服与希氏束起搏相关的所有困难。