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探讨 COVID-19 期间生物制剂和其他全身治疗药物使用建议:对现有皮肤科指南和患者登记处的回顾和比较。

Examining recommendations for the use of biologics and other systemic therapies during COVID-19: a review and comparison of available dermatology guidelines and patient registries.

机构信息

Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC, USA.

Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC, USA.

出版信息

J Dermatolog Treat. 2022 May;33(3):1208-1212. doi: 10.1080/09546634.2020.1808154. Epub 2020 Oct 30.

Abstract

BACKGROUND

The novel coronavirus (COVID-19) has an affinity for almost every organ system, including the skin. This review article will compile and compare dermatology guidelines related to the dermatologic care of patients during the COVID-19 pandemic.

OBJECTIVE

To review and compare the available guidelines and recommendations on use of biologics and other systemic therapies in dermatology patients.

METHODS

We conducted a search for guidelines and recommendations for dermatology providers, with specific attention to the management of biologics and non-biologic systemic agents during COVID-19. International and United States-based guidelines specific to the field of dermatology and guidance for healthcare providers were used as inclusion criteria. Available registries were included as well.

CONCLUSION

The guidelines stress a shared decision-making approach with risk-benefit analysis and treatment strategy modifications tailored to each unique patient case. The guidelines were all concordant with one another in highlighting the importance that patients should not discontinue their medications without first speaking with their providers.

摘要

背景

新型冠状病毒(COVID-19)几乎对所有器官系统都有亲和力,包括皮肤。这篇综述文章将汇编并比较与 COVID-19 大流行期间患者皮肤科护理相关的皮肤科指南。

目的

综述和比较皮肤科患者使用生物制剂和其他全身治疗的现有指南和建议。

方法

我们搜索了皮肤科医生的指南和建议,特别关注 COVID-19 期间生物制剂和非生物制剂全身药物的管理。将专门针对皮肤科领域的国际和美国指南以及医疗保健提供者的指南作为纳入标准。还包括了可用的登记处。

结论

这些指南强调了一种共同决策方法,包括风险效益分析和针对每个独特患者病例的治疗策略修改。这些指南都一致强调患者不应在未经与提供者交谈之前停止用药。

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