Vahey T N, Glazer G M, Francis I R, Li K, Dafoe D C, Aisen A M, Smid D M
Department of Radiology, University of Michigan Medical Center, Ann Arbor 48109.
AJR Am J Roentgenol. 1988 Mar;150(3):557-60. doi: 10.2214/ajr.150.3.557.
To determine the role of MR imaging in the assessment of pancreatic transplant rejection, we prospectively obtained 13 MR scans in nine transplant patients. The presence of rejection was verified pathologically by pancreatic transplant biopsies in five patients. In two additional patients, rejection was proved by concordant renal transplant biopsy as well as by compatible clinical and laboratory data. In the remaining two patients, in whom no biopsy was done, clinical and laboratory data showed no evidence of rejection. The mean T2 of the seven pancreata undergoing rejection was significantly elevated (86 msec) compared with the mean T2 of the two transplants not undergoing rejection (59 msec) (p less than .002). These preliminary results suggest that MR may be useful in the noninvasive diagnosis of pancreatic rejection.
为确定磁共振成像（MR）在评估胰腺移植排斥反应中的作用，我们前瞻性地对9例移植患者进行了13次MR扫描。5例患者通过胰腺移植活检在病理上证实存在排斥反应。另外2例患者，通过肾移植活检结果一致以及临床和实验室数据相符证实存在排斥反应。其余2例未进行活检的患者，临床和实验室数据未显示排斥反应迹象。与2例未发生排斥反应的移植胰腺平均T2值（59毫秒）相比，7例发生排斥反应的胰腺平均T2值显著升高（86毫秒）（p<0.002）。这些初步结果表明，MR可能有助于胰腺排斥反应的无创诊断。
