Department of Otorhinolaryngology and Head and Neck Surgery, First Faculty of Medicine, Charles University and Motol University Hospital, V Uvalu 84, 15006, Prague, Czech Republic.
Department of Pathology and Molecular Medicine, Second Faculty of Medicine, Charles University and Motol University Hospital, V Uvalu 84, 15006, Prague, Czech Republic.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021 Sep;165(3):342-345. doi: 10.5507/bp.2020.032. Epub 2020 Jul 20.
Low-grade fibromyxoid sarcoma (LGFMS) is a rare malignant tumor. Moreover, only 3 cases of LGFMS originating from the nasal cavity and/or paranasal sinuses have been published so far.
Two patients with histologically confirmed LGFMS of the maxillary sinus were primarily treated by open and endoscopic surgery. In one case adjuvant radiotherapy was indicated because of the uncertainty of the surgical margins.
Both surgeries were technically demanding and accompanied by significant bleeding from the tumors. Despite the extensive interventions there were no postoperative complications and no significant morbidity of the patients. There is no evidence of the disease 148 and 65 months after the treatment.
Regardless of the excellent post-treatment results, based on our experience, preoperative embolisation of the tumor should be considered prior to the surgical resection.
低度纤维黏液样肉瘤（LGFMS）是一种罕见的恶性肿瘤。此外，目前仅发表了 3 例源自鼻腔和/或鼻窦的 LGFMS。
对 2 例经组织学证实的上颌窦 LGFMS 患者行开放性和内镜手术进行初步治疗。由于手术切缘不确定，1 例患者需要辅助放疗。
两次手术均具有较高的技术难度，且肿瘤出血明显。尽管干预广泛，但术后无并发症，患者无明显发病率。治疗后 148 和 65 个月均无疾病证据。
根据我们的经验，无论治疗后结果如何，在手术切除前，应考虑对肿瘤进行术前栓塞。
