Helderman J H
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75235-9030.
Am J Kidney Dis. 1988 Feb;11(2):131-3. doi: 10.1016/s0272-6386(88)80196-3.
This report deals with the clinical application of monoclonal antibody techniques to fine needle aspiration biopsy (FNAB) of the renal transplant. The technique was deemed to be quite helpful in corroborating cell type analysis made by classical cytochemistry (Giemsa staining), and determination of the nature of the lymphoid subset at play in rejection. The role of activation marker analysis and class 2 alloantigen analysis in particular for rejection was also discussed.
本报告探讨了单克隆抗体技术在肾移植细针穿刺活检（FNAB）中的临床应用。该技术被认为在证实经典细胞化学（吉姆萨染色）进行的细胞类型分析以及确定参与排斥反应的淋巴细胞亚群的性质方面非常有帮助。还讨论了激活标志物分析和2类同种异体抗原分析在特别是排斥反应中的作用。
