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股骨头缺血性坏死的髓芯减压治疗结果

The Results of Core Decompression Treatment in Avascular Necrosis of the Femoral Head.

作者信息

Talmaç Mehmet Ali, Kanar Muharrem, Sönmez Mehmet Mesut, Özdemir Hacı Musatafa, Dırvar Ferdi, Tenekecioğlu Yüksel

机构信息

Department Orthopedics and Traumatology, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, Turkey.

Department Orthopedics and Traumatology, University of Health Sciences Metin Sabancı Baltalimanı Osteopathic Training and Research Hospital, İstanbul, Turkey.

出版信息

Sisli Etfal Hastan Tip Bul. 2018 Dec 28;52(4):249-253. doi: 10.14744/SEMB.2018.47135. eCollection 2018.

Abstract

OBJECTIVE

Avascular necrosis of the femoral head (AVNFH) is a progressive disease seen in young, active patients, leaving significant disability in the joint when untreated. We retrospectively examined the results of patients with early stage AVNFH who had been operated in our clinic.

METHODS

In our study, 65 hips of 46 patients were evaluated retrospectively. These patients were evaluated clinically by the Merle d'Aubigné-Postel Score and Harris Hip Score. The patients were radiologically staged according to the criteria by Ficat and Arlet with hip anterior-posterior and lateral graphs and magnetic resonance imaging.

RESULTS

The mean follow-up period of the patient group was 73 months, and the mean age of the patients was 35 years. Of these patients, 59% were female and 41% were male; 41% had bilateral and 40% had right hip involvement. One of the patients developed AVNFH while she was pregnant, 7 were idiopathic, and 38 (81%) developed AVNFH due to steroid use. According to the Ficat and Arlet classification, 18 hips were found to be stage 1, 37 hips stage 2, and 9 hips stage 3 during admission. From the etiological point of view, 81% of the patients developed AVNFH while using steroid and 19% had idiopathic AVNFH. As for clinical improvement of the patients, the Harris Hip Score increased from 58 to 90 in idiopathic patients and 55 to 83 among steroid users. The Merle d'Aubigné-Postel classification scores increased from 6 to 15 in the idiopathic group and from 6 to 13 among steroid users. Radiologically, according to the Ficat and Arlet stage, progression was seen in all stages. Of the patients, 38.8% in stage 1, 70.2% in stage 2, and 88.8% in stage 3 showed progression, whereas 20% demonstrated rapid progression and needed total hip prosthesis. All patients who demonstrated progression were on chronic steroid therapy. The mean time to conversion to total hip replacement was 27 months.

CONCLUSION

Osteonecrosis is a disease associated with high morbidity. Early diagnosis can reduce morbidity and improve a patient's quality of life. Core decompression has the effect of stopping the progression of AVNFH in the early (stage 1) stages, although it has a significant and long-term palliative effect in all stages. Most of the young and active patients with AVNFH still do not have any ideal method for treatment today, but core decompression in the early stages has been seen to reduce morbidity. It is a time-saving attempt before the final treatment, which is hip arthroplasty, is performed.

摘要

目的

股骨头缺血性坏死(AVNFH)是一种在年轻、活跃患者中出现的进行性疾病,若不治疗会导致关节严重残疾。我们回顾性研究了在我院接受手术的早期AVNFH患者的治疗结果。

方法

在本研究中,对46例患者的65个髋关节进行了回顾性评估。通过Merle d'Aubigné - Postel评分和Harris髋关节评分对这些患者进行临床评估。根据Ficat和Arlet标准,通过髋关节前后位和侧位X线片以及磁共振成像对患者进行放射学分期。

结果

患者组的平均随访期为73个月,患者的平均年龄为35岁。这些患者中,59%为女性,41%为男性;41%为双侧受累,40%为右侧髋关节受累。其中1例患者在怀孕期间发生AVNFH,7例为特发性,38例(81%)因使用类固醇而发生AVNFH。入院时,根据Ficat和Arlet分类,发现18个髋关节为1期,37个髋关节为2期,9个髋关节为3期。从病因学角度来看,81%的患者在使用类固醇期间发生AVNFH,19%为特发性AVNFH。至于患者的临床改善情况,特发性患者的Harris髋关节评分从58分提高到90分,类固醇使用者从55分提高到83分。Merle d'Aubigné - Postel分类评分在特发性组从6分提高到15分,在类固醇使用者中从6分提高到13分。放射学方面,根据Ficat和Arlet分期,各阶段均有进展。1期患者中有38.8%、2期患者中有70.2%、3期患者中有88.8%出现进展,而20%表现为快速进展,需要进行全髋关节置换。所有出现进展的患者均接受慢性类固醇治疗。转换为全髋关节置换的平均时间为27个月。

结论

骨坏死是一种发病率较高的疾病。早期诊断可降低发病率,提高患者生活质量。髓芯减压在早期(1期)阶段有阻止AVNFH进展的作用,尽管在所有阶段都有显著的长期姑息作用。如今,大多数年轻、活跃的AVNFH患者仍没有任何理想的治疗方法,但早期髓芯减压已被证明可降低发病率。在进行最终治疗(即髋关节置换术)之前,这是一种节省时间的尝试。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c851/7406557/5dff4e6e9839/MBSEH-52-249-g001.jpg

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