Hiesse C, Goldschmidt E, Santelli G, Charpentier B, Machover D, Fries D
Nephrology Department, University Paris-South, Hospital Paul Brousse, Villejuif, France.
Am J Kidney Dis. 1988 Feb;11(2):188-91. doi: 10.1016/s0272-6386(88)80211-7.
A bone marrow transplant recipient is described who had development of nephrotic syndrome in association with chronic graft-versus-host disease (GVHD) and on cyclosporine (CsA) treatment withdrawal. Renal biopsy revealed a membranous glomerulonephritis (MG). The possible relationship between this autoimmune disorder, the immunological features of GVHD in experimental animals, and the influence of CsA is discussed.
本文描述了一名骨髓移植受者，其在慢性移植物抗宿主病（GVHD）和停用环孢素（CsA）治疗后出现了肾病综合征。肾活检显示为膜性肾小球肾炎（MG）。本文还讨论了这种自身免疫性疾病、实验动物GVHD的免疫学特征以及CsA的影响之间可能存在的关系。
