一名接受尼洛替尼一线治疗的慢性髓性白血病患者的斋月禁食
Ramadan Fasting in a Patient with Chronic Myeloid Leukemia Receiving Nilotinib as Upfront.
作者信息
Al-Dubai Husam N, Yassin Mohammed A, Abdulla Mohammed A, Aldapt Mahmood S, Ghassoub Rola S
机构信息
Internal Medicine Department, Hamad General Hospital, HMC, Doha, Qatar.
Department of Medical Oncology/National Centre for Cancer Care and Research, HMC, Doha, Qatar.
出版信息
Case Rep Oncol. 2020 Jun 15;13(2):664-667. doi: 10.1159/000507508. eCollection 2020 May-Aug.
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm classically described as triphasic disease: chronic, accelerated, and blast crisis. There are many unmet needs and unanswered questions about CML. Intermittent fasting in patients with CML on tyrosine kinase inhibitors is among these unmet needs. Here we report the effect of intermittent fasting on response to nilotinib as upfront in a 49-year-old female Muslim who fasted during Ramadan and took her medication once instead of twice daily and remained in major molecular response.
慢性髓性白血病（CML）是一种骨髓增殖性肿瘤，传统上被描述为具有三个阶段的疾病：慢性期、加速期和急变期。关于CML存在许多未满足的需求和未解答的问题。在接受酪氨酸激酶抑制剂治疗的CML患者中进行间歇性禁食就是这些未满足的需求之一。在此，我们报告了一名49岁穆斯林女性在斋月期间禁食且将每日服药次数从两次减为一次，但仍保持主要分子学缓解的情况下，间歇性禁食对其使用尼罗替尼一线治疗反应的影响。
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