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在撒哈拉以南非洲人群中,STOPBANG评分对阻塞性睡眠呼吸暂停综合征筛查有效且与其特征相关。

The STOPBANG score is effective for obstructive sleep apnea syndrome screening and correlates with its features, in a sub-Saharan African population.

作者信息

Massongo Massongo, Balkissou Adamou Dodo, Kenyo Corine Kenne, Sawa Brice Nouga, Kanko Nadine, Pefura Eric Walter

机构信息

Pulmonology Service, Jamot Hospital Yaoundé, Yaoundé, Cameroon.

Higher Institute of Medical Technology of Nkolondom, Yaoundé, Cameroon.

出版信息

Pan Afr Med J. 2020 Jun 15;36:93. doi: 10.11604/pamj.2020.36.93.17805. eCollection 2020.

Abstract

INTRODUCTION

the STOPBANG score is an easy-to-use screening tool for obstructive sleep apnea (OSA), which has not been validated in sub-Saharan Africa (SSA). We sought to evaluate its diagnostic performance in Cameroun.

METHODS

this community-based study took place in a sub-urban area, from November 2015 to April 2016. Adults aged ≥19 years underwent a clinical assessment, including the STOPBANG and the Epworth sleepiness scale (ESS) questionnaires. A respiratory polygraph (RP) was performed on a randomly selected sample. Diagnosis performance included sensitivity (Se), specificity (Sp), and positive and negative predictive values (PPV and NPV). An association was sought between STOPBANG and OSA features.

RESULTS

a total of 3033 were interviewed, of whom 102 had a RP. Their mean age was 49.1±17.9 years, the sex ratio was 1 and the mean body mass index 29.1±6.1 kg/m. For OSA screening (apnea-hypopnea index (AHI) ≥5), the STOPBANG score at threshold 3 obtained: Se=82.9%, Sp=34.4%, PPV=45.9% and NPV=75.0%. For moderate-to-severe OSA (IAH ≥15), these values were 93.3%, 31.1%, 18.9% and 96.4% respectively. Furthermore, STOPBANG-based high risk of OSA correlated with AHI (9.1±10.7/hr vs 3.8±3.5/hr, p=0.0003) and oxygen desaturation index (6.4±7.9/hr vs 2.6±2.1/hr, p=0.0004). There was a non-significant association with ESS (6.3±5.3 vs 4.5±3.5, p=0.06).

CONCLUSION

in this Cameroonian population, the STOPBANG diagnostic performance did not differ from the original Caucasian one. It could therefore be proposed on a larger scale, since obesity and other OSA risk factors are increasing in SSA.

摘要

引言

STOPBANG评分是一种用于阻塞性睡眠呼吸暂停(OSA)的易于使用的筛查工具,尚未在撒哈拉以南非洲(SSA)得到验证。我们试图评估其在喀麦隆的诊断性能。

方法

这项基于社区的研究于2015年11月至2016年4月在一个郊区进行。年龄≥19岁的成年人接受了临床评估,包括STOPBANG和爱泼沃斯思睡量表(ESS)问卷。对随机抽取的样本进行了呼吸多导睡眠图(RP)检查。诊断性能包括敏感性(Se)、特异性(Sp)以及阳性和阴性预测值(PPV和NPV)。研究了STOPBANG与OSA特征之间的关联。

结果

共访谈了3033人,其中102人进行了RP检查。他们的平均年龄为49.1±17.9岁,性别比为1,平均体重指数为29.1±6.1kg/m²。对于OSA筛查(呼吸暂停低通气指数(AHI)≥5),阈值为3时STOPBANG评分的结果为:Se=82.9%,Sp=34.4%,PPV=45.9%,NPV=75.0%。对于中重度OSA(IAH≥15),这些值分别为93.3%、31.1%、18.9%和96.4%。此外,基于STOPBANG的OSA高风险与AHI相关(9.1±10.7次/小时对3.8±3.5次/小时,p=0.0003)以及氧去饱和指数相关(6.4±7.9次/小时对2.6±2.1次/小时,p=0.0004)。与ESS有非显著关联(6.3±5.3对4.5±3.5,p=0.06)。

结论

在这个喀麦隆人群中,STOPBANG的诊断性能与最初的白种人人群没有差异。因此,鉴于SSA地区肥胖和其他OSA风险因素在增加,可以更大规模地采用该评分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13de/7392869/e368ba7ed298/PAMJ-36-93-g001.jpg

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