Han Sang Beom, Liu Yu-Chi, Mohamed-Noriega Karim, Tong Louis, Mehta Jodhbir S
Department of Ophthalmology, Kangwon National University School of Medicine, Kangwon National University Hospital, Chuncheon, Republic of Korea.
Singapore National Eye Centre, Singapore.
J Ophthalmol. 2020 Jul 22;2020:3509064. doi: 10.1155/2020/3509064. eCollection 2020.
Traditional diagnostic tests for dry eye disease (DED), such as fluorescein tear film break-up time and the Schirmer test, are often associated with poor reproducibility and reliability, which make the diagnosis, follow-up, and management of the disease challenging. Advances in ocular imaging technology enables objective and reproducible measurement of changes in the ocular surface, tear film, and optical quality associated with DED. In this review, the authors will discuss the application of various imaging techniques, such as, noninvasive tear break-up time, anterior segment optical coherence tomography, in vivo confocal microscopy, meibography, interferometry, aberrometry, thermometry, and tear film imager in DED. Many studies have shown these devices to correlate with clinical symptoms and signs of DED, suggesting the potential of these imaging modalities as alternative tests for diagnosis and monitoring of the condition.
传统的干眼疾病（DED）诊断测试，如荧光素泪膜破裂时间和泪液分泌试验，往往重复性和可靠性较差，这使得该疾病的诊断、随访和治疗具有挑战性。眼部成像技术的进步能够客观且可重复地测量与干眼疾病相关的眼表、泪膜和光学质量的变化。在这篇综述中，作者将讨论各种成像技术的应用，如非侵入性泪膜破裂时间、眼前节光学相干断层扫描、活体共聚焦显微镜检查、睑板腺照相术、干涉测量法、像差测量法、温度测量法以及泪膜成像仪在干眼疾病中的应用。许多研究表明，这些设备与干眼疾病的临床症状和体征相关，这表明这些成像方式作为该疾病诊断和监测的替代测试具有潜力。
