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青少年精索静脉曲张。一个治疗难题。

Varicocele in youth. A therapeutic dilemma.

作者信息

Sayfan J, Soffer Y, Manor H, Witz E, Orda R

机构信息

Department of Surgery A, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Zerifin, Israel.

出版信息

Ann Surg. 1988 Feb;207(2):223-7. doi: 10.1097/00000658-198802000-00019.

DOI:10.1097/00000658-198802000-00019
PMID:3277548
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1493363/
Abstract

The need for treatment of asymptomatic varicocele in youth is controversial. In the current study testicular volume and seminal variables were evaluated in three groups: young varicocele patients with undetermined fertility potential, infertile varicocele patients, and a control group of young males. The testicular volume was determined by ultrasonographic measurements. The results revealed a significant loss of "testicular mass" in both varicocele groups compared with the control group. The seminal findings disclosed a severe disturbance of spermatogenesis in the older varicocele group, whereas in the younger varicocele patients only the total spermatic count was significantly depressed. This difference in severity of functional impairment between the younger and older varicocele groups possibly points towards progressiveness of damage to the testicles. A more decisive therapeutic approach to the young male with asymptomatic varicocele and unknown fertility status could be justified.

摘要

青少年无症状精索静脉曲张的治疗需求存在争议。在本研究中,对三组人群的睾丸体积和精液变量进行了评估:生育潜力未明的年轻精索静脉曲张患者、不育的精索静脉曲张患者以及年轻男性对照组。通过超声测量确定睾丸体积。结果显示,与对照组相比,两个精索静脉曲张组的“睾丸质量”均显著下降。精液检查结果表明,年龄较大的精索静脉曲张组精子发生严重紊乱,而在较年轻的精索静脉曲张患者中,仅精子总数显著降低。年轻和年长精索静脉曲张组在功能损害严重程度上的这种差异可能表明睾丸损伤具有渐进性。对于生育状况不明的无症状精索静脉曲张年轻男性,采取更果断的治疗方法可能是合理的。

相似文献

1
Varicocele in youth. A therapeutic dilemma.青少年精索静脉曲张。一个治疗难题。
Ann Surg. 1988 Feb;207(2):223-7. doi: 10.1097/00000658-198802000-00019.
2
Testicular volume and semen parameters in patients aged 12 to 17 years with idiopathic varicocele.12 至 17 岁特发性精索静脉曲张患者的睾丸体积和精液参数。
J Pediatr Surg. 2012 Feb;47(2):383-5. doi: 10.1016/j.jpedsurg.2011.11.035.
3
Significant worsening sperm parameters are associated to testicular hypotrophy in patients with a high grade varicocele.在重度精索静脉曲张患者中,精子参数显著恶化与睾丸萎缩有关。
Actas Urol Esp. 2015 Jul-Aug;39(6):392-5. doi: 10.1016/j.acuro.2014.08.005. Epub 2015 Feb 11.
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[Fertility prognosis associated to percutaneous testicular biopsy in infertile varicocele patients].[精索静脉曲张不育患者经皮睾丸活检的生育预后]
Rev Med Inst Mex Seguro Soc. 2008 Sep-Oct;46(5):543-50.
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Sperm concentration and forward motility are not correlated with age in adolescents with an idiopathic varicocele and symmetrical testicular volumes.在患有特发性精索静脉曲张且睾丸体积对称的青少年中,精子浓度和向前运动能力与年龄无关。
J Pediatr Surg. 2016 Feb;51(2):293-5. doi: 10.1016/j.jpedsurg.2015.10.080. Epub 2015 Nov 5.
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Image cytometry for quantitative analysis of DNA in the testes of infertile men with varicocele: comparison with flow cytometry.图像细胞术用于精索静脉曲张不育男性睾丸中DNA的定量分析:与流式细胞术的比较
J Urol. 1997 Jun;157(6):2370-4.
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[Varicocele and fertility--spermiographic and histologic findings].[精索静脉曲张与生育能力——精子学和组织学研究结果]
Z Urol Nephrol. 1986 Apr;79(4):229-39.
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[Bilateral microsurgical varicocelectomy in infertile men].[不育男性的双侧显微外科精索静脉曲张切除术]
Urologiia. 2004 May-Jun(3):21-5.
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Asymptomatic postpubertal male with equally sized normal testicles with palpable left varicocele.青春期后无症状男性,双侧睾丸大小正常,左侧精索静脉曲张可触及。
Asian J Androl. 2016 Mar-Apr;18(2):310. doi: 10.4103/1008-682X.161601.
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Early varicocelectomy by percutaneous scleroembolization improves seminiferous tubules spermatozoa release in the adolescent phase of testicular growth.经皮硬化栓塞术早期精索静脉结扎术可改善青春期睾丸生长阶段生精小管精子释放。
Andrologia. 2019 Aug;51(7):e13286. doi: 10.1111/and.13286. Epub 2019 Apr 14.

引用本文的文献

1
Relationship between varicocele grade, vein reflux and testicular growth arrest.精索静脉曲张分级、静脉反流与睾丸生长停滞之间的关系。
Pediatr Surg Int. 2008 Jun;24(6):727-30. doi: 10.1007/s00383-008-2143-7. Epub 2008 Apr 18.
2
Increased vasoconstrictor reactivity and decreased endothelial function in high grade varicocele; functional and morphological study.重度精索静脉曲张中血管收缩反应性增强及内皮功能降低:功能与形态学研究
Urol Res. 2003 Oct;31(5):323-8. doi: 10.1007/s00240-003-0343-0. Epub 2003 Jul 11.

本文引用的文献

1
Histological findings in testes with varicocele during childhood and their therapeutic consequences.儿童精索静脉曲张患者睾丸的组织学 findings 及其治疗后果。 需注意这里“findings”直接翻译为“发现”不太符合医学语境,结合上下文推测这里可能是指“检查结果”之类的意思,但按照要求未添加额外解释。
Eur J Pediatr. 1980 Mar;133(2):139-46. doi: 10.1007/BF00441582.
2
A new entity in varicocele subfertility: the "cremasteric reflux".精索静脉曲张性不育中的一个新因素:“提睾肌反流”。
Fertil Steril. 1980 Jan;33(1):88-90. doi: 10.1016/s0015-0282(16)44486-9.
3
Improved fertility after varicocele correction: fact or fiction?
精索静脉曲张矫正术后生育能力改善:事实还是虚构?
Fertil Steril. 1984 Aug;42(2):249-56.
4
The varicocele.精索静脉曲张
Fertil Steril. 1984 Jan;41(1):5-11. doi: 10.1016/s0015-0282(16)47530-8.
5
Left varicocele at puberty.青春期左侧精索静脉曲张。
Urology. 1983 Sep;22(3):271-4. doi: 10.1016/s0090-4295(83)80012-0.
6
Varicocele in youth.青少年精索静脉曲张
West J Med. 1983 Jun;138(6):832-4.
7
Prevalence of varicocele in young Israeli men.以色列年轻男性精索静脉曲张的患病率。
Isr J Med Sci. 1984 Nov;20(11):1099-100.
8
Seminal cytology in the presence of varicocele.精索静脉曲张情况下的精液细胞学
Fertil Steril. 1965 Nov-Dec;16(6):735-57. doi: 10.1016/s0015-0282(16)35765-x.
9
Varicocele in children and adolescents. An investigation of the incidence among Danish school children.儿童和青少年精索静脉曲张。丹麦学童发病率调查。
Scand J Urol Nephrol. 1971;5(1):27-32. doi: 10.3109/00365597109133569.
10
Measurement of human testicular consistency by tonometry.通过眼压测量法测量人类睾丸硬度。
Fertil Steril. 1985 Jun;43(6):911-6.