Vermeulen A, Vandeweghe M
Fertil Steril. 1984 Aug;42(2):249-56.
Fertility after varicocele correction by embolization of the vena spermatica in 62 subjects was compared with fertility in an untreated group (n = 20) of subjects with varicocele. One year after varicocele correction of infertile males with oligozoospermia, asthenozoospermia, or teratozoospermia but normal follicle-stimulating hormone levels, 15 of 62 had achieved a pregnancy; in the untreated group, 8 had achieved a pregnancy. Comparison of results by cumulative pregnancy rate analysis reveals that the pregnancy rate was only marginally higher in the treated group. Varicocele correction induced only a modest improvement of sperm quality; the severity of varicocele had no influence either on sperm characteristics or on the outcome of treatment. It is concluded that the effects of varicocele correction on the pregnancy rate can be seriously doubted and that large-scale prospective studies are urgently required to determine whether or not varicocele correction improves the pregnancy rate and which subjects could eventually benefit from the treatment.
对62名通过精索静脉栓塞术矫正精索静脉曲张后的生育能力，与20名未治疗的精索静脉曲张患者的生育能力进行了比较。在患有少精子症、弱精子症或畸形精子症但促卵泡生成素水平正常的不育男性精索静脉曲张矫正一年后，62人中有15人怀孕；在未治疗组中，有8人怀孕。通过累积妊娠率分析比较结果显示，治疗组的妊娠率仅略高。精索静脉曲张矫正仅使精子质量有适度改善；精索静脉曲张的严重程度对精子特征或治疗结果均无影响。结论是，精索静脉曲张矫正对妊娠率的影响很值得怀疑，迫切需要进行大规模前瞻性研究，以确定精索静脉曲张矫正是否能提高妊娠率以及哪些患者最终能从该治疗中获益。
