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酷似克罗恩病的胃肠道结核

Gastrointestinal Tuberculosis Mimicking Crohn's Disease.

作者信息

Rafael Maria Ana, Martins Figueiredo Luísa, Oliveira Ana Maria, Nuno Costa Mariana, Theias Manso Rita, Martins Alexandra

机构信息

Gastroenterology Department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.

Pathologic Anatomy Department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.

出版信息

GE Port J Gastroenterol. 2020 Jul;27(4):278-282. doi: 10.1159/000504719. Epub 2019 Dec 13.

DOI:10.1159/000504719
PMID:32775550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7383244/
Abstract

We present the case of a 24-year-old woman with complaints of abdominal pain, bloody diarrhea, and weight loss for 3 months. An outpatient colonoscopy revealed scattered ulcers, suggestive of Crohn's disease (CD). Histopathology also favored the diagnosis of CD. However, after admission to our hospital for further investigation, a chest radiograph revealed pulmonary cavitations. A computed tomography scan suggested the diagnosis of active pulmonary tuberculosis (TB). Therefore, a bronchofibroscopy, a total colonoscopy with ileoscopy, and an upper endoscopy were performed. Not only were acid-fast bacilli present in both bronchoalveolar lavage fluid and gastric juice, but also in colonic biopsies. A complete resolution of gastrointestinal symptoms was achieved 2 weeks after starting anti-TB drugs.

摘要

我们报告了一例24岁女性患者,她有腹痛、血性腹泻和体重减轻3个月的症状。门诊结肠镜检查发现散在溃疡,提示克罗恩病(CD)。组织病理学也支持CD的诊断。然而,在我院住院进一步检查后,胸部X线片显示肺部有空洞。计算机断层扫描提示活动性肺结核(TB)的诊断。因此,进行了支气管纤维镜检查、全结肠镜检查及回肠镜检查和上消化道内镜检查。不仅在支气管肺泡灌洗液和胃液中发现了抗酸杆菌,在结肠活检组织中也发现了抗酸杆菌。开始抗结核药物治疗2周后,胃肠道症状完全缓解。

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本文引用的文献

1
Differentiating Crohn's disease from intestinal tuberculosis.鉴别克罗恩病与肠结核。
World J Gastroenterol. 2019 Jan 28;25(4):418-432. doi: 10.3748/wjg.v25.i4.418.
2
Miliary Tuberculosis in a Crohn's Disease Patient: The Risk beyond the Screening.一名克罗恩病患者的粟粒性肺结核:筛查之外的风险。
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Meta-Analytic Bayesian Model For Differentiating Intestinal Tuberculosis from Crohn's Disease.用于区分肠结核和克罗恩病的Meta分析贝叶斯模型
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Am J Gastroenterol. 2016 Aug;111(8):1156-64. doi: 10.1038/ajg.2016.212. Epub 2016 Jun 14.
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Intestinal tuberculosis and Crohn's disease: challenging differential diagnosis.肠结核与克罗恩病:具有挑战性的鉴别诊断
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Abdominal tuberculosis of the gastrointestinal tract: revisited.胃肠道结核:再探讨
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Differentiation of Crohn's disease from intestinal tuberculosis by clinical and CT enterographic models.通过临床和CT小肠造影模型鉴别克罗恩病与肠结核
Inflamm Bowel Dis. 2014 May;20(5):916-25. doi: 10.1097/MIB.0000000000000025.