酷似克罗恩病的胃肠道组织胞浆菌病
Gastrointestinal Histoplasmosis Mimicking Crohn's Disease.
作者信息
Shojaei Esfandiar, Walsh Joanna C, Sangle Nikhil, Yan Brian, Silverman Michael S, Hosseini-Moghaddam Seyed M
机构信息
Division of Infectious Diseases, Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.
Department of Pathology and Laboratory Medicine, London Health Sciences Centre, Western University, London, Ontario, Canada.
出版信息
Open Forum Infect Dis. 2021 May 16;8(7):ofab249. doi: 10.1093/ofid/ofab249. eCollection 2021 Jul.
Disseminated histoplasmosis is a life-threatening disease usually seen in immunocompromised patients living in endemic areas. We present an apparently immunocompetent patient with gastrointestinal histoplasmosis who was initially diagnosed with biopsy-proven Crohn's disease. Following discontinuation of anti-inflammatory drugs and institution of antifungal therapy, his gastrointestinal illness completely improved. Specific fungal staining should be routinely included in histopathologic assessment of tissue specimens diagnosed as Crohn's disease.
播散性组织胞浆菌病是一种危及生命的疾病，通常见于生活在流行地区的免疫功能低下患者。我们报告一名看似免疫功能正常但患有胃肠道组织胞浆菌病的患者，其最初被活检证实为克罗恩病。停用抗炎药物并开始抗真菌治疗后，他的胃肠道疾病完全好转。对于诊断为克罗恩病的组织标本进行组织病理学评估时，应常规进行特异性真菌染色。
Zotero 插件